胡绪敬,王士明,奚文龙,贾克丽,刘国敏.A群脑膜炎奈瑟氏菌脂多糖抗原血清型在我国八省一市的分布[J].Chinese journal of Epidemiology,1984,5(4):195-198 |
A群脑膜炎奈瑟氏菌脂多糖抗原血清型在我国八省一市的分布 |
The Distribution of Lipopolysaccharide (LPS) Serotypes of N.meningitidis group A.in Eight Provinces and Cities in China |
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Abstract: |
本文报道应用改进的HAI试验方法调查A群NM LPS抗原的血清型。此分型方法简单,可重复性亦好,并且可以测定各型LPS抗原的HAI滴度。以此方法检查我国八省一市所分离的96株A群NM,其中90株(93.7%)可以分成三个血清型(L9、L10和L11),以L10型最多见,占80株(83.3%),在我国流行分布较广。本试验初步分析,自1973年以后,我国流脑的流行主要与A群NM L10型有关。 |
English Abstract: |
This paper reports the results of a revised technique of hemagglutination inhibition (HAI) test used in investigating lipopolysaccharide (LPS) sero-types of N.meningitidis group A.The technique of serotyping was simple and the experimental results were reproducible and the HAI titers of various LPS antigens could be determined Ninty-six strains of meningococci group A isolated from eight provinces and one municipality in China were examined with our revised HAI test.Among them,90 strains (93.7%) were divided into three serotypes (L9. L10. and L11).L10 accounted for 83.3% of all the strains studied and was found widely prevalent in China.The results of this preliminary study showed that LPS type 10 of N.Meningitidis group A had been associated with epidemic cerebrospinal menigitis prevalent since 1973 in China. |
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