| 陈宏材.用SpA协凝法快速检测脑脊液中脑膜炎球菌抗原[J].Chinese journal of Epidemiology,1985,6(2):122-124 |
| 用SpA协凝法快速检测脑脊液中脑膜炎球菌抗原 |
| Rapid Detection of Meningococcal Antigen in Cerebrospinal Fluid by SpA Coagglutination |
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| Abstract: |
| 用CoA法检测37份临床诊断为"流脑"患者脑脊液中脑膜炎球菌抗原,并与细菌培养法和CIE法比较,其阳性率分别为43.24%、32.43%和27.03%,以CoA法阳性率最高。发病1天者CoA法的阳性数可达11/20,其测得的抗原滴度相等或高于CIE法,是一种具有实用价值的诊断方法,值得推广。 |
| English Abstract: |
| Thirty-seven specimens of CSF from clinically diagnosed meningococcal meningitis patients were tested for meningococcal antigen by coagglutination technique, in which Staphylococcus aureus Cowan I was used as SpA producer. The coagglutination was compared with routine culture and counter current immunoelectrophoresis (CIE) methods. The percentage of positive result of coagglutination was the highest of three methods. The titre of meningococcal antigens by coagglutination was the same as, or higher than that by CIE. It showed that coagglutination may be applied for detecting meningococcal antigen in CSF. |
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