| 王海涛,蒋豫图,马静,朱明宝,张习坦.北京某郊区乙型肝炎的流行病学研究[J].Chinese journal of Epidemiology,1985,6(3):141-144 |
| 北京某郊区乙型肝炎的流行病学研究 |
| A Serocpidemiologic Study of Viral Hepatitis B in the Suburb of Beijing |
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| Abstract: |
| 从1982年6月到1983年6月我们研究了北京近郊-个农业生产大队HBV感染的自然史。1982年对全体人员的84%(491人)用固相放射免疫分析法(SPRIA)检测了HBV标记,HBsAg阳性率为7.3%,抗-HBs是36.7%,抗-HBc是45.6%,HBV总感染率52.3%。男性HBsAg阳性率是女性的1.5倍(8.9%对5.9%,P>0.05)。HBsAg阳性者中56%是15岁以下的儿童。抗-HBs、抗-HBc和总HBV感染率男女性都无显著差异。1983年复查了398人(81%)。191名在1982年HBV标记阴性者中有6人获得了HBV标记,HBV新感染率3.1%,6人都是亚临床感染。1982年HBsAg阳性的31人有28人在1983年变成了HBsAg慢性携带者,HBsAg慢性携带率占HBV感染者的13.6%。抗-HBs阳性者占HBV感染者的70%。 |
| English Abstract: |
The natural history of hepatitis B virus (HBV) infection was studied in a rural production brigade in the suburb of Beijing from June, 1982 to June, 1983.In 1982, 491 serum samples collected from 84% of members were tested for HBV markers by solid-radioimmunoassay (SPRIA).The prevalence rates of HBsAg, anti-HBs and anti -HBc were 7.3, 33.7 and 45.6 percent, respectively, and the HBV infection rate was 52.3 percent in tha population. The prevalence rate of HBsAg among the males was 1.5 times higher than that among the females (8.9% vs. 5.9%, P>0.1). of the HBsAg positive individuals, 56%were children under 15 years. There was not much difference between males and females in the rates of anti-HBs, anti-HBc and overall HBV infection.
Three hundred and ninety eight of 491 individuals who were tested in June,1982 were retested in June, 1933. Six of 191 individuals (3.1%) without any markers of HBV in 1982 acquired some of HBV marksrs; all of the infection were subclinical and symptomless. Twenty-eight of 31 persons (90.3%) being HBsAg positive in 1982 became chronic HBsAg carriers and the represented 14% of all persons infected by HBV.Persons having anti HBs consituted 70% of all the HBV infected. |
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