伤寒杆菌的耐药性与伤寒的爆发流行

郑庆斯; 陶香娣; 张东; 徐兆炜

Abstract

郑庆斯,陶香娣,张东,徐兆炜.伤寒杆菌的耐药性与伤寒的爆发流行[J].Chinese journal of Epidemiology,1987,8(6):340-342

伤寒杆菌的耐药性与伤寒的爆发流行

The Antimicrobial Resistance of S. typhi and Outbreak of Typhoid Fever

DOI：

KeyWord: 伤寒杆菌可传递性R质粒耐药性监测

English Key Word: S. typhi conjugative R plasmid Surveillance on antimicrobial resistance

FundProject:

Author Name	Affiliation
Zheng Qingsi	Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing
et al	Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing
张东	Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing
徐兆炜	Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing

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Abstract:

本文报道55株散发和38株爆发伤寒菌株的药物敏感试验、质粒检测及R质粒传递试验的结果。所有受检菌均出现不同程度的耐药现象,严重者耐药达8种之多;爆发株对常用抗菌素的耐药性明显高于散发株。R质粒的接合传递试验结果初步表明,散发株可传递性R质粒检测结果阴性,但发现一起爆发中,流行株携带有可传递性R质粒,由于检测菌株数尚少,其意义有待进一步探讨。

English Abstract:

This paper reported the results of antimicrobial resistance pattern plasmid profiles and conjugative R plasmid of 93 S. typhi isolates. All Strains were resistant to 2-8 drugs tested. The increase in the resistance to Cmp was compared between two groups of strains. The subgroup of isolates from outbreak were much more seriously than that unrelated outbreak. The results shown there was no conjugative R plasmidamong strains unrelatedoutbreak, but epidemiological strains in an outbreak were positive in the same test, thesignificance sould be distermined in further study since the numbor of strains tested were less.

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