Abstract
王言贵,陈向伟,于载畿,魏育林.单纯疱疹病毒II型与宫颈糜烂关系的血清流行病学研究[J].Chinese journal of Epidemiology,1988,9(4):214-216
单纯疱疹病毒II型与宫颈糜烂关系的血清流行病学研究
Seroepidemiological Survey of Herpes Simplex Virus Type 2 in Cervical Erosion Women
  
DOI:
KeyWord: 单纯疱疹病毒II型  宫颈糜烂  中和抗体
English Key Word: HSV-2  Cervical erosion  NT antibody
FundProject:
Author NameAffiliation
Wang Yangui Department of Microbiology, Shanxi Medical College, Taiyuan 
陈向伟 Department of Microbiology, Shanxi Medical College, Taiyuan 
于载畿 山西医学院妇产科教研室 
魏育林 山西医学院妇产科教研室 
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Abstract:
      本文从血清流行病学方面研究了单纯疱疹病毒II型(HSV-2)感染与宫颈糜烂发生的关系。结果发现,宫糜实验组HSV-2中和抗体的阳性检出率为39.4%,显著地高于正常对照组的阳性检出率(12.0%),经χ2检验,P<0.005。宫糜实验组HSV-2中和抗体的年龄分布,有随年龄的增长其HSV-2中和抗体的阳性检出率亦随之增加的趋势,至更年期后则下降。宫糜时,HSV-2中和抗体阳性与临床体征(宫糜类型:颗粒型、乳头型;宫糜面积:重度、中度)间未见有相关关系。根据上述结果作了简要讨论。
English Abstract:
      The rate of NT antibody positive to HSV-2 in cervical erosion group was 39.4%, significantly higher than that of the healthy control women group which was found to be 12.0% (P<0.005).
Age distribution of the NT antibodies of cervical erosion women to HSV-2 was examined. Among 71 cases, a tendency of increase of positive rate of antibody by age was observed except 45 to 55-year-old: 35.7% for 25 to 29-year-old, 38.5% for 30 to 34-year-old, 40.0% for 35 to 39-year-old, 46.7% for 40 to 44-year-old, 40.0% for 45 to 49-year-old, and 25.0% for 50 to 55-year-old respectively.
No correlation was observed between the serum positive rate and clinical type (papilliform, granuliform) or area of cervical erosion. The significance of these findings was discussed briefly.
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