李英.血吸虫病与大肠癌的地区相关分析[J].Chinese journal of Epidemiology,1988,9(5):265-268 |
血吸虫病与大肠癌的地区相关分析 |
Geographical Correlation Analysis between Schistosomiasis and Large Intestine Cancer |
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DOI: |
KeyWord: 血吸虫病 大肠癌 等级相关系数 |
English Key Word: Schistosomiasis colorectal cancer Rank correlation coefficient |
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Abstract: |
本文应用1974~1976年浙江省肿瘤死亡回顾调查和1975~1978年中国恶性肿瘤调查研究的资料以及中华人民共和国血吸虫病地图集,探讨了血吸虫病与大肠癌之间的统计学关系。地区相关分析结果表明,在我国和浙江省的血吸虫病流行区,血吸虫病发病率与大肠癌死亡率高低变化呈直线相关关系。我国南方12个省市自治区和浙江省嘉兴地区10个县的血吸虫病发病率与大肠癌死亡率间的等级相关系数分别为0.706和0.903,都具有非常显著的相关性,说明在我国血吸虫病严重流行地区血吸虫病可能是大肠癌高发的一个危险因素。 |
English Abstract: |
The correlation between Schistosomiasis and colorectal cancer was investigated with statistical analysis by using incidence rate of Schistosomiasis and the mortality of colorectal cancer. It was found that there exists a linear correlation between mortality rate of colorectal cancer and incidence rate of schistosomiasis in endemic areas of south china, especially in areas of higher schistosomiasis prevalence. The rank correlation coefficients of 12 provinces in south china and that of 10 counties in Jiaxing prefecture of Zhejiang province are 0.706 (P<0.01) and 0.903 (P<0.001) respectively. Similar results were obtained in the 9 counties with the high prevalence of schistosomal infestation in Zhejiang province (r s=0.983, P<0.0005). It was suggested that the schistosomal infestation might be one of the risk factors in carcinogenesis of large intestine in the serious endemic areas of schistosomiasis. |
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