流行性出血热人群隐性感染研究

米尔英; 赵习芳; 张法宽; 梅志强; 任珂; 王乃昌; 吴雪云

Abstract

米尔英,赵习芳,张法宽,梅志强,任珂,王乃昌,吴雪云.流行性出血热人群隐性感染研究[J].Chinese journal of Epidemiology,1989,10(1):11-13

流行性出血热人群隐性感染研究

Studies on Inapparent Infection of Epidemic Hemorrhagic Fever in Population of Shanxi Province

DOI：

KeyWord: 流行性出血热隐性感染抗体测定

English Key Word: Epidemic hemorrhagic fever napparent infection Antibody detection

FundProject:

Author Name	Affiliation
Mi Erying	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
赵习芳	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
张法宽	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
梅志强	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
任珂	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
王乃昌	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan
吴雪云	Solitary and Anti-epidemic Station of Shanxi Province, Taiyuan

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Abstract:

对山西省家鼠型流行性出血热疫区非疫区4 873份正常人血清进行流行性出血热IgG抗体检测,检出阳性238份,总阳性率4.88%。疫区流行性出血热隐性感染率为5.48%.不同流行强度疫区的隐性感染有高度显著性差异。并对隐性感染抗体滴度进行了统计,用百分位数法(P₉₅)求出正常人隐性感染抗体滴度的上限值为1:315。初步提出临床病例单份血清IgG抗体滴度达1:320以上时,结合临床表现可对病人作出特异诊断。

English Abstract:

Detection for IgG antibody to virus of epidemic hemorrhagic fever (EHF) in sera from healthy people in Shanxi province were carried out by IFAT.Two hundred thirty eight of 4873 serum samples were antibody-positive. Total positive rate was 4.88%. The inapparent infection rate of EHF in residents of endemic areas was 5.48%.There was a statistically significant difference of epidemic strength among different counties.Based on the analysis of antibody titers of positive sera,value of upper limit (P95) of antibody titre for inapparent infection was 1:315.It was suggested that the antibody titre of 1:320 by IFAT in a single sample of serum from patient with clinical manifestations of EHF might be used as a criteria for specific diagnosis of EHF.

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