Abstract
赫宗玉,俞顺章,李俊卿,毛光辉,王佳懿.过敏性肺炎爆发流行的调查[J].Chinese journal of Epidemiology,1989,10(3):129-132
过敏性肺炎爆发流行的调查
Investigation on an Outbreak of allergic Pulmonary alveolitis
  
DOI:
KeyWord: 过敏性肺炎  肺炎爆发  霉菌过敏
English Key Word: Allergic alveolitis  Outbreak of alveolitis  Allergy for funguses
FundProject:
Author NameAffiliation
He Zongyu Shanghai University Medical 
俞顺章 Shanghai University Medical 
李俊卿 上海日晖医院 
毛光辉 上海日晖医院 
王佳懿 上海日晖医院 
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Abstract:
      上海一所小学校,在1986年元旦前夕,10天内在教职工中突然发生肺炎20例,占职工总人数的42.6%(20/47)。学生137人与教师接触密切未发现病例。师生均以症状和胸片肺部异常为诊断标准。流行病学分析结果表明,爆发为一次暴露于共同致病因子所致。发病与接触病人无关,与集体分购甘蔗时,接触并吸入所附尘埃有关。痰液检验及粪便虫卵计数检验均未发现寄生虫感染的证据。血清中IgE含量测定,恢复期病人血清IgE增高显著。甘蔗表面霉菌的分离培养,以青霉菌、毛霉菌、红酵母及酵母样菌为优势菌株。吸入霉尘可能是此次肺炎爆发之因。
English Abstract:
      20 allergic alveolitis cases occurred abruptly within 10 days among teachers at a primary school in Shanghai. The cases make up 42.6% (20/47) of total staffs of the school. No patient discovered in pupils (137) though they had enough chance to contact with their teachers suffering the disease.
Roentgenography and clinical findings were criferia of diagnosis.
The findings of epidemiologic survey showed that the outbreak was caused by a single exposure of same agent, probably associated with sugarcanes.
The result of examinations in laboratory shows:
1.The content of IgE increased significantly in serum of convalescence patients.
2.Penicillum and Mucor were found as prevaling fungus strains beening isolated from the surfase of sugarcanes.
3.Did not find ascarid larva in spurum nor eggs in feces.
In this paper we infered reasonably tha. breathing of dust with funguses may be the cause of the outbreak.
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