| 肺炎球菌分型研究协作组.我国18省(市)肺炎球菌血清型及其感染的流行病学研究[J].Chinese journal of Epidemiology,1989,10(3):133-137 |
| 我国18省(市)肺炎球菌血清型及其感染的流行病学研究 |
| Serotypes and Epidemiological Study of Pneumococcal Infection in 18 Provinces (Cities) in China |
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| DOI： |
| KeyWord: 肺炎球菌病 血清型 流行病学 |
| English Key Word: Pneumococcal disease Serotype Epidemiology |
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| Abstract: |
| 1982到1985年期间,在我国18个省(市)由482例肺炎球菌病病人中分离到482株肺炎链球菌,其中来自肺炎67株,脑膜炎169株,中耳炎246株。其血清型及流行病学的研究结果如下:肺炎球菌性肺炎、脑膜炎及中耳炎病例分别占每1 000例细菌感染相应疾病病例数的14.26、79.08和68.14例,大多数感染为婴幼儿。肺炎的病死率为16.4%,脑膜炎为16%。所有分离的肺炎链球菌均用分型血清(Statens Seruminstitut Copenhagen)进行了检定。主要血清型是5、6、1、19、2和14,占分型菌株总数的56.8%(274株)。5型是最主要血清型,占分型菌株总数的13.3%(63株)。 |
| English Abstract: |
| During the years 1982 to 1985, 482 strains of S.pneumoniae were isolated from 482 patients of pneumococcal diseases in 18 provinces (cities) in China. There were 67 strains from the patients of pneumococcal pneumonia, 169 strains from pneumococcal meningitis and 246 strains from pneumococcal otitis media. Their serotypes and epidemiology were studied with following results:The rate of pneumococcal pneumonia, meningitis and otitis media was 14.26 cases, 79.08 cases and 68.14 cases per 1000 homologous disease cases, respectively.Most of the infections occurred at the infants while 73.7% pneumococcal meningitis, 63% otitis media and 40.3% pneumonia were in ≤ 3 age group.The mortality of patients with pneumococcal pneumonia was 16.4% and with pneumococcal meningitis was 16%. All of isolates of S. pneumoniae were identified using typing antisera (Statens Seruminstitut, Copenhagen). The main types were 5, 6, 1, 19, 2 and 14, which accounted for 56.8%(274 strains) of total number of strains. Type 5 was the most main serotype and accounted for 13.3% (63 strains). |
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