婴儿尿和母乳巨细胞病毒分离的横断面调查

张玫瑰; 叶正中; 冯婉玲; 丘翠芳

Abstract

张玫瑰,叶正中,冯婉玲,丘翠芳.婴儿尿和母乳巨细胞病毒分离的横断面调查[J].Chinese journal of Epidemiology,1990,11(4):226-228

婴儿尿和母乳巨细胞病毒分离的横断面调查

The Cross-Section Study of CMV Isolation in Infants, Urine and Mothers, Breast Milk

Received:May 17, 1989 Revised:September 05, 1989

DOI：

KeyWord: 巨细胞病毒尿母乳

English Key Word: CMV Urine Breast milk

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Author Name	Affiliation
Zhang Meigui	The Central Laboratory, Guangzhou Medical College
叶正中	The Central Laboratory, Guangzhou Medical College
冯婉玲	The Central Laboratory, Guangzhou Medical College
丘翠芳	The Central Laboratory, Guangzhou Medical College

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Abstract:

本文对广州地区健康婴儿尿和母乳进行巨细胞病毒(CMV)分离。183例婴儿尿CMV阳性率为56.8%,其中2月龄、3~6月龄、7~12月龄的阳性率分别为27.7%、60.8%和75.5%。73例母乳的CMV阳性率为47.9%,其中产后2月内、3~6月和7~12月的母乳阳性率分别为51.8%、45.7%和45.5%。67例婴儿尿和母乳配对进行分离,其阳性率分别为56.7%和52.2%,其中母乳阳性的婴儿尿阳性率为(24/35),母乳阴性的婴儿尿阳性率为43.7%,二者之间有显著性差异(χ²=4.19,P<0.05)。本研究结果表明广州地区母乳和婴儿尿CMV分离阳性率较高;喂养含有CMV的母乳可能是生后一岁内婴儿获得性感染方式之一。

English Abstract:

One hundred and eighty-three normal healthy infants' urine and 73 mothers' breast milk were examined for CMV acquired infection by virus isolation. The total positive rate of infection in infants' urine and breast milk were 56.8% (104/183) and 47.9% (35/73) respectively. Among the 67 mother-baby pairs, consumption of infected and uninfected breast milk led to CMV infection of 68.5% (24/35) and 43.79% (14/32) of the infants respectively, which showed significant difference (χ²=4.19, P<0.05). Our study showed that infected breast milk feeding may be a way of CMV acquired infection during the first year of life, and we should pay more attention to it.

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