HIV-1抗体检测初筛试剂质量评价

王哲; 曾毅; 孙新华; 甄宏元; 涛波; 邢雅珊; 林旭东; 赵文萍; 强来英; 纪燕; 赵煌君; 王炳涛; 陈光; 周科清; 贺延平; 刘忠武; 李建国; 杨德文; 郑玉臣

Abstract

王哲,曾毅,孙新华,甄宏元,涛波,邢雅珊,林旭东,赵文萍,强来英,纪燕,赵煌君,王炳涛,陈光,周科清,贺延平,刘忠武,李建国,杨德文,郑玉臣.HIV-1抗体检测初筛试剂质量评价[J].Chinese journal of Epidemiology,1991,12(6):369-373

HIV-1抗体检测初筛试剂质量评价

Evaluation of Screening Reagents for Detection of HIV-1 Antibody

DOI：

KeyWord: HIV-1检测试剂评价初筛试验

English Key Word: HIV-1 Testing Reagents Evaluation Screening Test

FundProject:

Author Name	Affiliation
Wang Zhe	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
曾毅	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
孙新华	卫生部卫生防疫司急传处
甄宏元	甘肃省卫生防疫站
涛波	内蒙古自治区卫生防疫站
邢雅珊	哈尔滨卫生检疫所
林旭东	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
赵文萍	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
强来英	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
纪燕	AIDS Research and Detection Center, Chinese Academy of Preventive Medicine
赵煌君	甘肃省卫生防疫站
王炳涛	甘肃省卫生防疫站
陈光	甘肃省卫生防疫站
周科清	甘肃省卫生防疫站
贺延平	甘肃省卫生防疫站
刘忠武	内蒙古自治区卫生防疫站
李建国	内蒙古自治区赤峰市卫生防疫站
杨德文	哈尔滨卫生检疫所
郑玉臣	哈尔滨卫生检疫所

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Abstract:

用134份HIV-1抗体阳性血清和1 468份阴性血清对国内常用的PA、LA、ELISA(Wellcome)、IE、QWB等初筛试剂进行质量评价,用部分血清进行了国产试剂比较和快速方法的比较,并对混合血清检测的方法进行了评价。结果表明,上述试剂中ELISA、PA、IE和QWB试剂质量较好,能满足国内需要,并能进行混合血清检测。

English Abstract:

Evaluation of screening reagents including PA, ELISA (Wellcome), IE, QWB, and LA by using 134 sera from HIV-1 infected persons and 1468 sera from normal persons. Comparing of domestic reagent and rapid methods by using part of the sera, and evaluating pooling sera method. The results suggested that the quality of PA, IE, QWB and the ELISA were enough for using in HIV testing in China and could be used for pooling method.

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