南京市心肌病流行病学研究协作组.南京市人群原发性心肌病的发病率调查[J].Chinese journal of Epidemiology,1992,13(4):193-196 |
南京市人群原发性心肌病的发病率调查 |
A Population-based Study on Incidence of Idiopathic Cardiomyopathy in Nanjing, 1985~1989 |
Received:September 14, 1991 Revised:December 05, 1991 |
DOI: |
KeyWord: 原发性心肌病 流行病学调查 发病率 |
English Key Word: Idiopathic cardiomyopathy Epidemiological survey Incidence rate |
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Abstract: |
原发性心肌病(ICM)是一组原因未明的心肌疾病。本病在自然人口中的分布情况,迄今尚不清楚。本文就南京市区60岁以内全部人口于1985~1989年期间发病的ICM逐个进行登记,并参照1980年WHO专家委员会所拟定的ICM命名与分类核实诊断,符合标准者计有275例,5年平均年发病率为2.6/10万,标化率2.1/10万。其中扩张型(IDCM)134例,肥厚型(IHCM) 132例,年均发病率均为1.3/10万,标化率分别为1.1/10万和0.9/10万。各型ICM的发病率随年龄增长而明显增高,20岁以后尤为明显。ICM男性年发病率3.0/10万,女性为2.2/10万。标化率分别为2.3/10万和1.8/10万,男性明显高于女性,尤以IHCM较为显著。5年间ICM的总的发病率有逐年增加趋势,其中IHCM更显著。本文调查结果为国内首次提供了以大范围自然人口为基础的ICM发病率。 |
English Abstract: |
The epidemiology of idiopathic cardiomyopathy (ICM) is largely unknow among Chinese population. The purpose of this study was to document the incidence of ICM in the entire residents aged less than 60 years in Nanjing city during the five year period from 1985 to 1989. Using the case registed method it was identifid that 275 new cases of ICM collecting from all of the clinically diagnosed outpatients and inpatients in the 14 related hospitals within the city among 2098, 175 residents for years 1985~1989.Over all incidence rate was 2.6 per 100000 person-years, the age-and sex-adjusted average annual rate being 2.1 per 100000 directly according to the standardized population of China in 1964 (95% confidence interval 1.9~2.2).This incidence rate was increased from 1.7 per 100000 in 1985 to 3.3 per 100000 in 1989 and progressively increasing with aging especially in the groups over 20 years old. Among these 275 patients with ICM, 134 were classified to idiopathic dilated cardiomyopathy (IDCM) and 132 to idiopathic hypertrophic cardmyopathy (IHCM). Both the average annual incidence rates of IDCM and IHCM were 1.3 per 100000 and the age-and sex-adjusted rates were 1.1 per 100000 (95%CI 0.9~1.2) in IDCN and 0.9 per 100000 (95%CI 0.8~1.0) in IHCM, respectively. The incidence rate of ICM in male was 3.0 significantly higher than 2.2 per 100000 in female especially in IHCM. The result of this survey is first provided with incidence data of ICM on a broad general population-based study in our country and may be of value in further studing its epidemiology and etiology. |
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