| 权力敏,王有苗,张南霞,吕清云,阎惠云,秦克锋,喻启桂,曹茂开,汪美先.青岛地区不同职业人群中生殖器单纯疱疹病毒感染情况的流行病学调查[J].Chinese journal of Epidemiology,1993,14(5):262-265 |
| 青岛地区不同职业人群中生殖器单纯疱疹病毒感染情况的流行病学调查 |
| Investigation on the Incidence of Genital Herpes in Different Professional Groups in Qingdao |
| Received:November 20, 1992 Revised:March 06, 1993 |
| DOI： |
| KeyWord: 生殖器疱疹 单克隆抗体 酶连接免疫吸附测定 职业 |
| English Key Word: Genital herpes Antibodies monoclonal ELISA Professional |
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| Abstract: |
| 在青岛地区对随机抽查的11个不同职业及两个特殊人群(妊娠、宫颈癌)中1148份生殖器分泌物,应用单克隆抗体双夹心法酶联免疫吸附试验(McAb-ELISA),分型检测标本中单纯疱疹病毒(HSV)抗原,总阳性率为22.6%,其中HSV-1占2.5%,HSV-2占20.0%。在不同性别中,男性标本中HSV抗原阳性率为24.2%,女性为21.5%,两者无显著性差异。特殊职业中,长途贩运司机标本中,HSV抗原阳性率为48.0%,个体饭店从业人员为39.2%,个体旅馆从业人员为28.4%,个体商贩为27.2%,均明显高于对照的国营集体职业人群,且感染以HSV-2为主。年龄分布则以性活跃期(19~50岁)感染率高。宫颈癌患者HSV抗原阳性率为38.2%,其中HSV-2占36.6%,表明HSV-2与宫颈癌可能有一定关系。妊娠妇女HSV抗原阳性检出率为8.2%,因此HSV对优生优育的影响应进一步研究。男性特殊职业人群HSV感染率高,为本地区生殖器疱疹的一个流行特点,应引起足够重视。 |
| English Abstract: |
| Genital herpes is one of 8 legally reportable sexually transmitted diseases (STD) in China. Using a HSV antigen ELISA kit we detected and typed HSV antigen in 1148 clinical specimens collected from the genital organs (penis, cervix, vagina and vulva) of 446 men and 702 women in Qindao and divided into 11 different professional and 2 special groups (patients with cervial cancer and pregnant women). The highest positive rate of HSV antigen was found among long-distance transport drivers (48.0%). The second and third high positive rates were among waiters and waitresses in private, restaurants (39.2%) and patients with cervial cancer (38.2%). The positive rates among self-employed retailers and employees in private inns and restaurants were notably higher than those among employees in state-run shops, restaurants and hotels. And, the positive rate among workers was higher than that among peasants. There was no notable difference between the positive rate of HSV antigen among men (24.2%) and that among women (21.5%). But the incidence of HSV-2 infection was much higher than that of HSV-1 infection. The results indicate that some special prefessional groups have high rates of genital HSV infection. More attention needs to be paid to these special groups in order to control sexually transmitted herpes diseases. |
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