Abstract
陈维清,吴系科,张衍文.两种类型老年高血压病因差异的研究[J].Chinese journal of Epidemiology,1994,15(1):23-26
两种类型老年高血压病因差异的研究
A Study on the Difference of Etiology between Two Types of Hypertension in Old People
Received:March 24, 1993  Revised:June 04, 1993
DOI:
KeyWord: 高血压  流行病学  危险因素
English Key Word: Hypertension  Epidemiology  Risk factors
FundProject:
Author NameAffiliation
Chen Weiqing 中山医科大学流行病学教研室 510089 广州市 
Wu Xike 安徽医科大学流行病学教研室 
Zhang Yanwen 安徽医科大学流行病学教研室 
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Abstract:
      通过对现况调查中诊断的94例老年单纯收缩期高血压和67例非单纯收缩期高血压,与135例血压正常者进行病例对照研究,筛选出各自的危险因素。然后,对它们作比较分析,探讨是否存在着差异。在研究的年龄、性别、婚姻状况、吸烟、饮酒、精神创伤、高血压家族史、身高、体重、体重指数、血糖水平、血清胆固醇、甘油三脂和高密度脂蛋白胆固醇等18个变量中,经单因素非条件Logistic回归分析。结果表明:老年ISH的发病与高血压家族史、精神创伤、年龄、血糖水平有关,体重指数、体重、吸烟、饮酒、精神创伤、血清总胆固醇水平是NISH发病的危险因素。进一步多因素非条件Logistic回归分析显示:高血压家族史、精神创伤、血糖水平先后进入ISH方程。体重指数、吸烟、精神创伤、血清总胆固醇水平依次入选NISH的方程。研究揭示ISH和NISH的病因存在差异,从病因学的角度支持ISH是不同于NISH的独特综合症。
English Abstract:
      Basing on the prevalence survey, 94 cases were diagnosed as simple senile systolic hypertension and 67 cases as non simple senile systolic hypertension, and 136 persons with normal blood pressure were sampled as control. Two case-control studies were conducted, then the etiologic factors of two types of hypertension were compared. Amomg age, sex, smoking, drinking, mental incidence, family history of hypertension, body height, body weight, body weight index, blood sugar, TC, TG, HDL-c, etc., a total of 18 factors, mono variate unconditional logistic regression analysis showed that the occurrence of ISH associated with age, family history of hypertension, mental incidence and blood sugar, and that the risk factors of NISH were body weight index, body weight, smoking, drinking, mental incidence, and TC. Further multi-inconditional logistic regression turned out that mental incidence, family history of hypertension and blood sugar entered the model of ISH, and that the body weight index, smoking, mental incidence, blood and TC entered the model of ISH. The study showed that the etiologic factors of ISH differed from those of NISH, which was a syndrome differed from NISH.
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