Abstract
柴锋,张荣珍.脊髓灰质炎疫苗全程免疫儿童发病因素的探讨[J].Chinese journal of Epidemiology,1994,15(5):267-270
脊髓灰质炎疫苗全程免疫儿童发病因素的探讨
Study on Factors Affecting Vaccination Effect of Poliomyelitis Vaccine
Received:September 02, 1993  Revised:December 28, 1993
DOI:
KeyWord: 脊髓灰质炎  全程免疫  对比研究  条件Logistic回归分析
English Key Word: Poliomyelitis  fully vaccinated  Comparative study  Condition logistic regression
FundProject:
Author NameAffiliation
Chai Feng Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing 102206 
Zhang Rongzhen Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing 102206 
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Abstract:
      为探讨脊髓灰质炎(简称脊灰)全程免疫病例发病的危险因素,我们于1992年6~10月份在广西、河南、江苏三省的部分县、乡中进行了一次1:2配比的病例对照研究,通过对收集到的资料进行单因素和多因素条件Logistic回归分析认为,引起全程免疫儿童发病的危险因素包括团体因素和个体因素两大类。团体因素主要指与冷链及卫生服务有关的因素,为脊灰全程服苗病例发病所特有的危险因素。个体因素主要指一些社会行为因素,为免疫及未免疫儿童共同的发病危险因素。此外,服用5次及5次以上脊灰疫苗是一个保护性因素。提示在不断提高接种率的同时,应注意提高接种质量。
English Abstract:
      We carried out this 1:2 matched case-control study in some counties and townships in Guangxi, Henan and Jiangsu provences from June to October in 1992 to find the risk factors of poliomyelitis incidence among fully vaccinated children. Then we processed the collected data with individual and multiple condition logistic regression analysis and found the risk factors of poliomyelitis incidence among fully vaccinated children included two kinds, the community factors and the individual factors. The community factors which related to the cold chain and health services. They are the special risk factors for fully vaccinated children. The individual factors are the common risk factors for both fully vaccinated and unvaccinated children.
In addition, children received five or more doses of TOPV was a favorable factor against poliomyelitis. It was showed that we must improve vaccination quality while rising TOPV coverage continually.
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