Abstract
杨英奎,王秀红,郭晓尉,胡丕英.高碘高氟对儿童智力及碘氟代谢影响的研究[J].Chinese journal of Epidemiology,1994,15(5):296-298
高碘高氟对儿童智力及碘氟代谢影响的研究
Effects of High lodine and High Fluorine on Children's Intelligence and the Metabolism of lodine and Fluorine
Received:May 07, 1993  Revised:November 05, 1993
DOI:
KeyWord: 高碘性甲状腺肿  氟斑牙  促甲状腺激素
English Key Word: High iodine goiter  Dental fluorosis  Thyroid stimulating hormone (TSH)
FundProject:
Author NameAffiliation
Yang Yingkui Shandong Provincial Institute of Endemic Disease Control, Jinan 250014 
Wang Xiuhong Shandong Provincial Institute of Endemic Disease Control, Jinan 250014 
Guo Xiaowei Shandong Provincial Institute of Endemic Disease Control, Jinan 250014 
胡丕英 Shandong Provincial Institute of Endemic Disease Control, Jinan 250014 
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Abstract:
      笔者对高碘高氟地区儿童智力及碘氟代谢进行了调查研究,结果表明,“双高病区”居民甲状腺肿患病率为3.80%,儿童甲状腺肿大率为29.80%,氟斑牙居民患病率为35.48%,儿童为72.98%。学生平均智商(IQ)为76.67±7.75,但智力低下者占16.67%。尿碘、尿氟分别为816.25±1.80μg/L和2.08±1.03mg/L,明显高于对照点。甲状腺吸181碘率明显低于对照点,3小时、24小时的值分别为9.36±1.55%和9.26±4.63%,血清促甲状腺激素(TSH)值明显高于对照点,说明高碘高氟对机体有严重的危害性,应引起注意。
English Abstract:
      An investigation on children's intelligence and the metabolism of iodine and fluorine in high iodine and fluorine regions was carried out. The results were as follows.
In high iodine and high fluorine areas, the thyroid enlargement prevalence rate among inhabitants and that among children were 3.8% and 29.8%, respectively. The dental fluorosis prevalence rate among inhabitants and that among children was 35.48% and 72.9%, respectively. The pupils' average intelligence quotient (IQ) was 76.67±7.75, slightly lower than the control point, but that of low intelligent pupils was 16.7%. The urinary iodine and urinary fluoride were 816.25±1.80 μg/L and 2.08±1.03mg/L, respectively, markedly higher than the control point. The thyroid iodine-131 (181I) uptake rate was markedly lower than the control point. The values at 3h and 24h were 9.36±1.55% and 9.26±4.63%, respectively. The serum TSH was obviously higher than the control point. These results indicate that high iodine and high fluorine exert severe damage to human body.
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