| 张景华,袁林,杨永弘,吴广琴,余桑洁,秦宇红,高薇,Iontova IM.600名健康妊娠妇女及其所娩新生儿B族链球菌带菌情况的研究[J].Chinese journal of Epidemiology,1995,16(1):36-39 |
| 600名健康妊娠妇女及其所娩新生儿B族链球菌带菌情况的研究 |
| Perinatal Colonization of Group B Streptococcus: A Study in 600 Cases in Beijing Tiantan Hospital |
| Received:March 23, 1994 Revised:August 29, 1994 |
| DOI： |
| KeyWord: 围产期 B族链球菌 带菌率 |
| English Key Word: Perinatal Group B streptococcus Carriage |
| FundProject:本课题得到北京市自然科学基金和卫生部科研基金资助 |
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| Abstract: |
| 对天坛医院600例产妇及其所娩新生儿B族链球菌(GBS)带菌情况进行调查,结果表明,8%产妇和6.7%的新生儿围产期带有GBS,总带菌率为13%。GBS阳性产妇早产和低体重儿的发生率较GBS阴性者为多,其既往发生流产的平均次数也较多。但本组没有发现GBS阳者携带者的胎膜早破和IUGR的发生率较阴性者高。分离的GBS主要为Ⅲ型,其次为Ⅰa型。抗生素敏感试验结果表明,对所有抗生素有耐药者均有一半以上菌株,其中对青霉素和庆大霉素耐药者高达90%以上,推测与国内滥用抗生素有关,将给临床选药带来一定困难,应引起重视。 |
| English Abstract: |
| An epidemiologic study of perinatal colonization of group B streptococcus(GBS)was carried out.Six hundred mother-infant pairs were studied at Beijing Tiantan Hospital.Maternal carriage rate of GBS was 8% with a neonatal colonization rate of 6.7%. Overall perinatal carriage rate was 13%. Women with perinatal colonization showed prone to have more prematured and low birth weight babies. We did not find that perinatal colonization was associated with prolonged rupture of membranes and IUGR in our study group. Serotypical study showed that most frequent GBS type isolated from the carriers was Ⅲ, followed by Ⅰa.Antibiotic sensitivity study showed that more than half of the GBS strains were resistant to the antibiotics a severe problem which might have caused by abuse in this country. |
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