| 周曾芬,张永生,王玉明,罗家洪,查学安,崔蓉,周崇斌.云南云县彝族、汉族地区幽门螺杆菌感染的流行病学调查[J].Chinese journal of Epidemiology,1997,18(1):18-21 |
| 云南云县彝族、汉族地区幽门螺杆菌感染的流行病学调查 |
| Seroprevalence of Helicobacter pylori Infection among Yi and Han Nationalities in Yunxian County, Yunnan Province |
| Received:March 15, 1996 Revised:May 27, 1996 |
| DOI： |
| KeyWord: 幽门螺杆菌 流行病学 酶联免疫吸附试验 |
| English Key Word: Helicobacter pylori Epidemiology ELISA |
| FundProject: |
| Author Name | Affiliation | | Zhou Zeng-fen | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | Zhang Yong-sheng | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | Wang Yu-ming | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | 罗家洪 | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | 查学安 | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | 崔蓉 | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 | | 周崇斌 | 1 Department of Digestion, The First Affiliated Hospital of Kunming Medical College, Kunming 650031 |
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| Abstract: |
| 在云南云县彝族、汉族地区用整群抽样方法对1184名自然人群进行前瞻性幽门螺杆菌（Hp）感染的血清学检测，并对其中325名同时检测抗-HAV IgG。结果发现：Hp总感染率为51.10%；彝、汉族感染率无差异。Hp感染随年龄增长而增加；饮用河水和生水明显高于饮用井水、自来水和开水；饲养家畜（禽）者明显高于未饲养者；吸毒者明显高于非吸毒者。Hp感染与HAV感染呈平行关系。多因素logistic最后筛选出饮用水源、饮水习惯、养鸡、养猪、养狗、吸毒和大蒜为Hp感染的7个重要流行因素。提示饮水是Hp感染的重要传播媒介；似支持Hp感染的动物来源理论和粪-口传播的观点；经常食用大蒜可起到长期人群防治Hp感染的作用。 |
| English Abstract: |
| Under cluster sampling, an early serum essay of helicobacterpylori (Hp) infection among 1084 healthy people, was carried out. Out of them, 325 among the Yi and Han Nationalities at Yunxian County of Yunnan Province were given a simultaneous test of anti-HAV IgG. The results were as follows:overall Hp infection rate was 51.1%; no difference of the infection was observed between the Yis and the Hans; the prevalence of Hp antibody went up with age; Higher rates were detected among those who drank river water or unboiled-water than among those who drank tap water, well water or boiled water, from poultry raisers than from non-poultry raisers and with drug abusers than with non-drug abusers. Hp infection showed a parallel relation to HAV infection. Finally, seven main epidemic factors were sifted from multi-factor logistic analysis namely source of drinking water, drinking habit, chicken-raising, pig-keeping, dog-breeding, drug-abusing and consumption of garlic. All these findings suggested that drinking water was an important vehicle of Hp infection. Our research data seems to have lend support to both fecal- oral transmission viewpoint and the hypothesis that Hp infection derives from animals. Frequent intake of garlic may serve as an agent in long-term prevention of Hp infection among people in this area. |
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