| 于普林,姚媛,杨泽,沈志卫,朱晓平,高芳坤.老年Ⅱ型糖尿病患者增殖型视网膜病变的多因素分析[J].Chinese journal of Epidemiology,1997,18(5):286-288 |
| 老年Ⅱ型糖尿病患者增殖型视网膜病变的多因素分析 |
| Multifactor Analysis on Proliferative Retinopathy in Elderly Patients with Type Ⅱ Diabetes |
| Received:May 20, 1997 Revised:June 21, 1997 |
| DOI： |
| KeyWord: 老年人 增殖型糖尿病视网膜病变 多因素分析 |
| English Key Word: Elderly Proliferative Diabetic retinopathy Multifactor analysis |
| FundProject: |
| Author Name | Affiliation | | YU Pu-lin | Beijing Hospital, Ministry of Health, People's Republic of China, Beijing 100730 | | Yao Yuan | 河北任丘华北石油钻井二公司医院 | | Yang Ze | Beijing Hospital, Ministry of Health, People's Republic of China, Beijing 100730 | | 沈志卫 | Beijing Hospital, Ministry of Health, People's Republic of China, Beijing 100730 | | 朱晓平 | 水利部北京总医院 | | 高芳坤 | Beijing Hospital, Ministry of Health, People's Republic of China, Beijing 100730 |
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| Abstract: |
| 为探讨各种危险因素对老年Ⅱ型糖尿病增殖型视网膜病变（PDR）的影响，应用多元逐步回归方法对98例老年Ⅱ型糖尿病有关PDR的危险因素进行分析。结果表明：（1）老年Ⅱ型糖尿病PDR的病程长于非糖尿病视网膜病变（DR）（P<0.01）；（2） PDR高血压、冠心病的并发率高于非PDR （P均<0.01）；尿素氮（P<0.01）、肌酐（P<0.05）、总胆固醇（P<0.01）、糖化血红蛋白Al （P<0.01）不同程度的高于非DR；PDR尿蛋白及微量白蛋白的排泄率高于非DR患者。（3）多因素分析提示：影响PDR的危险因素依次为：尿素氮、糖尿病病程、糖化血红蛋白Alc、高血压、尿蛋白和（或）微量白蛋白和总胆固醇。因此，为预防Ⅱ型糖尿病PDR的发生和发展，除有效的控制血糖外，还应把控制血压，减轻肾脏损害放在重要位置。 |
| English Abstract: |
| To evaluate the importance of different risk factors and their mutual interactions in the occurrence of proliferative diabetic retinopathy (PDR) in the elderly patients with type Ⅱ diabetes, an investigation was carried out on the relationship between PDR and various risk factors in 98 elderly cases of type Ⅱ diabetes by way of stepwise regression analysis method. Results showed:(1) the average course of PDR was longer than that of diabetic patients without diabetic retinopathy (P<0.01). Patients with PDR had higher values of BUN (P<0.01), Cr(P<0.05),GHbAlc(P<0.01) and TC(P<0.01) than those without retinopathy. Patients with PDR had higher coincidences of hypertension, coronary artery disease, proteinuria and urine microalbumin than those without retionpathy (P<0.01) respectively, (2) muhifactor analysis showed that BUN was one of the most important variables positively correlated with PDR, second to it in orders were the course of diabetes militus, GHhAlc, hypertention, proteinuria and urine microalbumin and TC. Conclusion:To prevent the occurrence and progress of PDR in the elderly patients with type Ⅱ diabetes, it is important not only to control blood sugar, but to control blood pressure and relieve renal damage. |
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