一起空调系统导致上呼吸道感染样军团病爆发的调查

马小燕; 王玉琴; 彭晓旻; 唐耀武; 楮天新; 周婉馨; 陈立泉; 万超群

Abstract

马小燕,王玉琴,彭晓旻,唐耀武,楮天新,周婉馨,陈立泉,万超群.一起空调系统导致上呼吸道感染样军团病爆发的调查[J].Chinese journal of Epidemiology,1998,19(4):200-204

一起空调系统导致上呼吸道感染样军团病爆发的调查

nvestigation of An Legionnaires' Disease Outbreak Associated with Contaminated Air - Conditioning System

Received:December 13, 1997 Revised:March 17, 1998

DOI：

KeyWord: 军团菌病空调系统爆发

English Key Word: Legionnaires' disease Air-conditioning system Outbreak epidemic

FundProject:

Author Name	Affiliation
Ma Xiaoyan	Department of Epidemiology, Beijing Municipal Center for Hygiene and Epidemic Control， Beijing 100013
Wang Yuqin	北京市东城区卫生防疫站
Peng Xiaoming	Department of Epidemiology, Beijing Municipal Center for Hygiene and Epidemic Control， Beijing 100013
Tang Yaowu	Department of Epidemiology, Beijing Municipal Center for Hygiene and Epidemic Control， Beijing 100013
Zhu Tianxin	Department of Epidemiology, Beijing Municipal Center for Hygiene and Epidemic Control， Beijing 100013
Zhou Wanxing	北京市东城区卫生防疫站
Chen Liquan	北京市东城区卫生防疫站
Wan Chaoqun	中国预防医学科学院流行病学微生物学研究所

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Abstract:

1997年6月北京某写字楼员工发生一起上呼吸道感染样(上感洋)疫情。为查明爆发原因, 采用流行病学病例-对照调查研究方法, 分别对病例组、对照组进行嗜肺军团菌(Lp)抗体1～14型血清学检测, 并对大厦空调系统采样进行细菌学培养检测。结果:该次爆发疫情的扁桃体炎罹患率为61.86%, 上感罹患率34.62%, 统计学检验发热与扁桃体关系密切(χ²=77.88, P<0.01);上感病例Lp9、10、12、14四型抗体阳性率为45.94%, 四组对照前述四种抗体的阳性比例分别为3/15、6/17、0/15、0/16;空调冷凝水培养Lp阳性。证明这是一起以空调系统为媒介由Lp9、12引起的上感样军团菌病爆发。

English Abstract:

An outbreak of upper respiratory infection (influenza-like syndrom) took place among the staff members of a large office building in Beiiing, June, 1997. To understand the cause of the outbreak, with a case-control study with serological antibodies detection against serogroup 1 to 14 of Legionnaires' disease bacteria (LDB) and bacteriological test and culture on samples collected from the air-conditioning system of the office building was performed. The findings showed that the attack rates of tongillitis and upper respiratory infection were 61.86% and 34.62% respectively. The relation was statistically significant between the symptoms of fever and tonsillitis in the cases (χ² =77.88, P0.01). The positive rates of LDB antibodies on serogroups 9, 10, 12, 14 were 45.94% in the cases of upper respiratory infection and 3/15, 6/17, 0/15, 1/16 respectively in the four controls groups. Condensied water samples from an air-conditioning system showed that Legionella Pneumophila was positive. Evidence showed that it was an outbreak resulting from LDB serogroup 9 and 12, accompanied by upper respiratory infection related to air-conditioning system contaminated by LDB. This was the first report Lp infection associated with an air-conditioning system in Cbina.

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