Abstract
赵扬冰,史宗道,刘立岷,吴星宇,敬静,李宏江.成都地区女性乳腺癌危险因素的病例对照研究[J].Chinese journal of Epidemiology,1999,20(2):91-94
成都地区女性乳腺癌危险因素的病例对照研究
Matched case-control study for detecting risk factors of Breast Cancer in women living in Chengdu
Received:July 27, 1998  Revised:September 24, 1998
DOI:
KeyWord: 乳腺癌  危险因素  病例对照研究
English Key Word: Breast cancer  Risk factor  Case-control study
FundProject:
Author NameAffiliation
ZHAO Yangbing First University Hospital,West China University of Medical Sciences,Chengdu 610041 
SHI Zongdao 华西医科大学临床流行病学资源培训中心 
LIU Limin First University Hospital,West China University of Medical Sciences,Chengdu 610041 
吴星宇 南京鼓楼医院 
敬静 First University Hospital,West China University of Medical Sciences,Chengdu 610041 
李宏江 First University Hospital,West China University of Medical Sciences,Chengdu 610041 
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Abstract:
      目的 调查成都地区女性乳腺癌危险因素,为确定高危人群、提出预防措施提供依据。方法 对过去3年中成都地区经病理证实的乳腺癌265例进行1:1配对病例对照研究。结果在单因素分析中,达到显着性水平的危险因素为行经期≥35年、服用避孕药、良性乳腺疾病史、被动吸烟及常食用蜂王浆等,达到显着性水平的保护因素为哺乳及常食豆类食品。条件logistic多元回归分析显示,重要的有统计学显着意义的乳腺癌危险因素是良性乳腺疾病史、被动吸烟,重要保护性因素是常食豆制品及哺乳。结论 成都地区女性乳腺癌重要危险因素为良性乳腺疾病史及被动吸烟。
English Abstract:
      ObjectiveTo detect the risk factors of breast cancer in women living in Chengdu in order to identify high risk population and to conduct proper interventions.MethodsA matched case-control study was performed in 265 cases w ith breast cancer who lived in this area.ResultsIn the univariate analysis, menarche to menopause period ≥35 years,taking oral contraceptives,history of benign breast diseases, passive smoking,and syrup drinking are the statistically significant risk factors of breast cancer,whereas breast feeding and soybean food consumption are protective factors.Conditional logistic multivariate analysis revealed that history of benign breast diseases and passive smoking are risk factors while soybean food products and breast feeding are protective factors.,Conclusion The risk factors of breast cancer in women living in Chengdu are history of benign breast diseases and passive smoking.
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