| 凌斌华,庄辉,李奎,杨永芳,李盛,马为民,王跃民.我国不同人群输血传播病毒感染调查[J].Chinese journal of Epidemiology,1999,20(5):277-279 |
| 我国不同人群输血传播病毒感染调查 |
| Detection of transfusion transmitted virus(TTV)in different populations of China |
| Received:March 26, 1999 Revised:April 17, 1999 |
| DOI： |
| KeyWord: 输血传播病毒 聚合酶链反应 肝炎病毒非甲-庚型 |
| English Key Word: Transfusion transmitted virus(TTV) Polymerase chain reaction(PCR) Non A-E hepatitis virus |
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| Abstract: |
| 目的：了解不同人群输血传播病毒 (TTV)的感染状况。方法：采用套式PCR法检测血清标本中TTVDNA,并对其中 1株TTV的部分基因序列进行了测定。结果：不同人群TTVDNA阳性率分别为:正常体检人群 10.3%,献血员 43.7%,吸毒者 15.6%,血液透析病人5 4.4%,妓女 65.0%,慢性丙型肝炎病人 2 5.0%,非甲～庚型肝炎 0/ 11。结论：TTV在各类人群中均有较高的感染率. |
| English Abstract: |
| Objective：To investigate the prevalence of transfusion transmitted virus(TTV)in different populations of China.Methods： TTV DNA was detected in sera collected from different populations by nested PCR.Partial gene of a TTV isolate was directly sequenced.Results：The prevalences of TTV in various populations were as follows:10.3%(31/301)in general population when receiving physical checkup;43.7%(14/32)in blood donors;15.6%(5/32)in intravenous drug addicts;54.4%(6/11)in hemodialysis patients;65%(13/32)in prostitutes;25%(4/16)in patients with chronic hepatitis C.None of the 11 patients with non A-G hepatitis was detected TTV DNA.Conclusion：High prevalence of TTV infection was found in different populations of China. |
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