人类免疫缺陷病毒血源传播问题的探讨

朱彪; 吴南屏; 强来英; 邵一鸣

Abstract

朱彪,吴南屏,强来英,邵一鸣.人类免疫缺陷病毒血源传播问题的探讨[J].Chinese journal of Epidemiology,2000,21(2):140-142

人类免疫缺陷病毒血源传播问题的探讨

The serologic study on the blood transmission origin of HIV

Received:August 29, 1999

DOI：

KeyWord: 人类免疫缺陷病毒乙型肝炎病毒丙型肝炎病毒血源传播

English Key Word: HIV HBV HCV Blood spread

FundProject:

Author Name	Affiliation
ZHU Biao	Department of Infectious Diseases the First Hospital of Zhejiang University, Hangzhou 310003, China
WU Nanping	Department of Infectious Diseases the First Hospital of Zhejiang University, Hangzhou 310003, China
QIANG Laiying	卫生部艾滋病预防与控制中心艾滋病参比实验室
邵一鸣	卫生部艾滋病预防与控制中心艾滋病参比实验室

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Abstract:

目的　探讨人类免疫缺陷病毒 (HIV)血源传播来源问题. 方法　收集全国各地HIV阳性血清 6 2份, 其中献血员血清 2 7份, 静脉吸毒者血清35份, 用EIA法进行HBV、HCV血清学检测. 结果　HIV感染者HBV总感染率为 53. 2%(33/62) 抗 -HCV阳性率为95. 2% (59/62). HIV、HBV、HCV三重感染率为51. 6% (32/62), HIV、HCV和HIV、HBV二重感染率分别为27. 4%(17/62)和1. 6%(1/62). 献血员中HBV总感染率44. 4%(12/27), 抗 -HCV阳性率 10 0 % (27/27) 静脉吸毒者中HBV总感染率60. 0%(21/35), 抗 -HCV阳性率91. 4%(32/35). 经统计学处理, 两人群HBV感染率与抗 -HCV阳性率差异无显著性 (P>0. 05). 对两人群中HIV、HBV、HCV三重、双重、单一感染率分析发现, 两人群间差异也无显著性 (P>0. 05). 结论　结果提示, HIV感染献血员和HIV感染静脉吸毒者HCV感染率很高两人群在感染HIV、HBV、HCV高危因素上存在着一定的内在联系, 静脉吸毒可能是引起我国HIV血源传播的主要根源

English Abstract:

Objective To study the origin of HIV blood spread in China. Methods Markers of HBV and HCV in 62 HIV-infections sera (27 blood donors and 35 i. v. drug users) were detected by EIA. Results The Results show that the total HBV infection was 53. 2%(33/62) and anti-HCV positive 95. 2 %(59/62). Super-infection of HIV、HBV、HCV was 51. 6%(32/60) and super-infection of HIV、HCV and HIV、HBV were 27. 4 %(17/62) and 1. 6 %(1/62). Comparing the markers of HBV and anti-HCV between blood donors and i. v. drug users, there was no statistical significant difference( P 0. 05 ). The super- infection of HIV、HBV、HCV and HIV、HCV and HIV、HBV were also no statistical differences ( P 0. 05 ) between two groups. Conclusion Resnlts indicated that a common infection mechanism might exist between Chinese HIV- infection blood donors and i. v. drug users.

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