| 周玢,洪震,黄茂盛,曾军,金美华.上海市城乡人群痴呆患病率调查[J].Chinese journal of Epidemiology,2001,22(5):368-371 |
| 上海市城乡人群痴呆患病率调查 |
| Prevalence of dementia in Shanghai urban and rural area |
| Received:December 27, 2000 |
| DOI： |
| KeyWord: 痴呆 患病率 阿尔茨海默病 |
| English Key Word: Dementia Prevalence Alzheimer' s disease |
| FundProject:国家“九五”科技攻关项目(969060501) |
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| Abstract: |
| 目的调查上海市城乡≥55岁人群中痴呆及其主要类型的患病率。方法采用分层多级整群抽样方法确定调查对象。共抽取22个居委会和14个村委会的55岁及以上的居民17018人。调查采用二阶段法,采用统一调查表和标准化调查用语,按名单入户调查。第一阶段用简易精神状态量表(minimentalstateexamination,MMSE)粗筛,第二阶段为诊断性检查,以60～64岁老人的MMSE测验成绩的第十百分位数值为分界值,对检查筛查阳性者及4%的阴性对象进行成套的神经心理测试。在半年后对进入第二阶段及临界者进行复查并确诊。结果≥55、≥65、≥70岁组人群痴呆患病率分别为3.0%、4.32%、5.29%,标化后分别为2.03%、3.78%、5.48%,其中阿尔茨海默病(Alzheimer’sdisease,AD)占72%,血管性痴呆(vasculardementia,VaD)占20.5%,城市和农村均以AD患病率高于VaD。上述各年龄组AD标化患病率为1.37%、2.71%、4.13%。≥55岁人群男女AD患病粗率分别为1.41%和2.78%,标化率分别为0.97%和1.67%。结论上海市城乡≥55岁人群痴呆患病率为3.0%。AD患病率高于VaD。 |
| English Abstract: |
| Objective To study the prevalence and epidemiological characteristics of dementia and their major types in people aged 55 years and old in urban and rural area, Shanghai. Methods A sample with 17 018 residents aged 55 years and above from 22 urban and 14 rural communities was drawn through a stratified multiple stage cluster sampling. A door to door three phase procedure was used to investigate the prevalence of dementia. In 1997 and 1998, A brief memory testing by MMSE was administered to all participants. In phase 2, those who scored below the cutoff points and four percent of those whose score was in the normal range were interviewed to identify dementia through a set of diagnostic examinations according to the DSM IV criteria. In phase 3, a follow up program was conducted in 1998 for all persons who was involved in phase 2 to identify those with Alzheimer's dementia (AD) and vascular dementia (VaD) by NINCDS ADRDA and NINDS AIREN criteria. Results Of the targeted sample, 15 910 ( 94.2 %) were interviewed. The overall prevalence of dementia was 3.0% in individuals aged 55 years and above, 4.32 % in those aged 65 years old and 5.29 % in those aged 70 years and above. The age adjusted prevalence rates of dementia were 2.03 %, 3.78% and 5.48 % respectively among the age groups mentioned above. For AD the age adjusted prevalence rates were 1.37 %, 2.71 % and 4.13 % for individuals in above age groups. Of all types of dementia, AD was accounted 72%, followed by VaD the second. The prevalence of AD was 1.41 % in man comparing to 2.78 % in woman. The age specific prevalence of AD increased with age. Conclusion The prevalence of dementia was 3.0 % in individuals aged 55 years in urban and rural areas in Shanghai. Alzheimer's disease was more frequent than VaD. |
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