| 崔君兆.中国TORCH 研究进展[J].Chinese journal of Epidemiology,2001,22(6):462-464 |
| 中国TORCH 研究进展 |
| A casecontrol study on attempted suicide |
| Received:February 12, 2001 |
| DOI： |
| KeyWord: 危险因素 自杀未遂 病例对照研究 精神疾病 |
| English Key Word: Risk factors Attempted suicides Case-control study Mental illness |
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| Abstract: |
| TORCH 是一组致畸微生物, T 即弓形虫(tox oplasma,
TP), R 即是风疹病毒(rubella virus, RV), C 即巨细胞病毒
(cy tomeg alo viruses, CMV), H 即单纯疱疹病毒(herpes simplex
virus, HSV), O 即其他(other, O), 这是一组宫内感染致胎儿
先天畸形、死胎、早产、流产、智力发育异常等的微生物, 有些
感染儿虽出生时未发现异常, 但在以后儿童期出现先天性耳
聋、脉络膜视网膜炎、视力下降、先天性心脏病、智力低下等。西方报道:出生畸形发生率为2 %～ 3 %, 两年后增加到4 %～6 %。我国卫生部1986～ 1987 年在全国29 个省、市、自治区对1 243 284名围产儿进行监测, 发现先天畸形儿16 172例,畸形发生率为1.3 %。杨茵[ 1] 报道对613 名孕产妇作TORCH-IgM 检测(ELISA)正常妊娠者阳性率为15.89 %(以
HSV1 阳性率为高5.93 %), 异常妊娠者阳性率为41.31 %(以HSV1 阳性率17.23% 为最高), 后者显著高于前者(P <0.05)。贾杰报道海南产妇血中IgG 阳性率以CMV 96.4 %
为最高(新生儿为93.6%), HSV 为95.7 %(新生儿为95.6%), RV 为84.3%(新生儿为82.6 %), TP 为22.6 %(新生儿为6.4 %), 7 例畸形儿中有3 例确定为CMV 感染, 2 例为RV 感染, 2 例病原难以确定;9 例流产孕妇中3 例为RV感染, 2 例为CMV 感染, 1 例为HSV, 1 例可能为习惯性流
产。 |
| English Abstract: |
| ObjectiveTo assess the independentrisk factors of attempted suicidemot the improtance of mentat ittness as a risk factor. Methods Detaited assessmen ts of 152 suicide attempterstreated in generat hospitats and 152 matched controts through questionaires. Resutts The rate of mentatillness in the suicide attempters' group was significantly higher than that in the controt group(37.7%versus 4. 0%, paired Chi square一45.45, P< 0. 001).Corxtitiona1 togistic; regression identified threeindependent predictors of suicidat behavior: severe acute stress(OR=67. 47, 95% CI: 8. 85--514. 56),presence of mentat ittness(OR=13. 8 5, 95% CI: 2. O1一95. 55)·and immense psychotogicat effect of negative tife events in the f>rior vear(OR=5. 30 95% CI: 1.1 2-26. 08).Conctusion Mentat illness is an important risk factor of attempted suicides but not an essertiat pre-condition of suicide attempts. It is important to estabtish a nationat、suicidesprevention plan that which is pertinent to the condiitions in China. |
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