| 韩磊,唐青,赵秀芹,西条政幸,陶晓霞.巴楚县2001年新疆出血热疫情的血清学证实[J].Chinese journal of Epidemiology,2002,23(3):179-181 |
| 巴楚县2001年新疆出血热疫情的血清学证实 |
| Serologic studies of Xinjiang hemorrhagic fever in Bachu county, 2001 |
| Received:July 18, 2001 |
| DOI： |
| KeyWord: 新疆出血热 流行病学 血清 克里米亚刚果出血热 |
| English Key Word: Xinjiang hemor rhagic fever Sero-epidemiology Crimean-Congo hemorrhagic fever |
| FundProject:国家自然科学基金资助项目(39870680) |
| Author Name | Affiliation | | HAN Lei | Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | TANG Qing | Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | ZHAO Xiuqin | Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China | | Masayuki Saijo | 日本国立感染症研究中心 | | TAO Xiaoxia | Institute for Infectious Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China |
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| Abstract: |
| 目的 以血清流行病学方法调查新疆出血热 (XHF)病人、易感人群和主要宿主动物中疾病的感染情况. 方法 分别收集2001年4～6月新疆巴楚县临床诊断为XHF的病人血清、易感人群血清和主要宿主动物的血清, 用研制的诊断试剂以酶联免疫吸附试验 (ELISA)检测XHF特异性IgG和IgM抗体 ;用抗原捕获ELISA检测XHF病毒抗原. 结果 病人血清IgG抗体阳性率为39. 62%(21/53), IgM抗体阳性率为20. 75%(11/53), 抗原捕获ELISA有1份血清为XHF抗原阳性 ;易感人群血清IgG抗体阳性率为21. 05%(4/19), IgM抗体检测和抗原捕获ELISA全部为阴性 ;羊血清IgG抗体阳性率为70%(56/80). 结论 血清流行病学研究证实该次疫情确系XHF, 流行地区人畜均有较高水平的隐性感染. |
| English Abstract: |
| Objective To investigate the situation of Xinjiang hemorrhagic fever (XHF) in patients who have been diagnosed as XHF by clinical Methods and to predict the condition in people who were liable to infection and in the host animals. Methods Sera collected from XHF patients and some peasants under the risk of contracting the disease, followed by checking the specific antibody against XHF with IgG ELISA and IgM capture ELISA, and XHF viral antigen with antigen capture ELISA. In addition, 80 sheep/goats serums were collected from two places where there were more XHF cases and specific IgG antibody against XHF checked by ELISA method. Results Positive rate of IgG and IgM antibodies were 39. 62 % (21/53) and 20. 75 % (11/53) respectively in the serums of patients; one patient's serum showed XHFV antigen positive by antigen capture ELISA. IgG antibody positive rate for peasants' sera was 21. 05 % (4/19), but IgM antibody detection showed negative for all sera. In sera from 80 sheep and goats, 70%(56/80) showed IgG positive. Conclusion Results showed that XHF broke out in Bachu county from April to June 2001 while recessive infection of the disease remained serious. |
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