性别间和家庭聚集的幽门螺杆菌感染的Meta分析

万毅; 徐勇勇; 薛富波; 樊代明

Abstract

万毅,徐勇勇,薛富波,樊代明.性别间和家庭聚集的幽门螺杆菌感染的Meta分析[J].Chinese journal of Epidemiology,2003,24(1):54-57

性别间和家庭聚集的幽门螺杆菌感染的Meta分析

Meta-analysis on Helicobacter pylori infection between sex and in family assembles

Received:December 11, 2001

DOI：

KeyWord: 幽门螺杆菌性别家庭聚集 Meta分析

English Key Word: Helicobacter pylori Sex Family assembles Meta- analysis

FundProject:国家教育部骨干教师计划;国家自然科学基金资助项目 ( 30024002 )

Author Name	Affiliation
Wan Yi	Department of Health Statistics, The Fourth Military Medical University, Xian 710032, China
Xu Yong-yong	Department of Health Statistics, The Fourth Military Medical University, Xian 710032, China
Xue Fu-bo	Department of Health Statistics, The Fourth Military Medical University, Xian 710032, China
Fan Dai-ming	第四军医大学第一附属医院消化内科, 西安 710032

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Abstract:

目的：综合分析并探讨幽门螺杆菌感染情况。方法：运用Meta分析方法对幽门螺杆菌性别间和家庭聚集的研究进行综合定量分析。结果：性别间幽门螺杆菌感染率有细微差别 ( 95% CI :0.0579～ 0.0963 ); 父母均阳性子女幽门螺杆菌感染率较父母均阴性者为高 ( 95 % CI:0.3378～0.5042 )。结论：幽门螺杆菌感染率存在性别差异和家庭聚集现象, 幽门螺杆菌流行病学研究涉及很多方面, 但均缺乏足够调查和证据, 尚需进一步研究。

English Abstract:

Objective： To understand and analyze the infection situation of Helicobacter pylori ( H.pylori). Methods： Extensively reviewing Chinese liter ature collecting the related with electronic documents in combination with manual retrieve and using Meta-analysis to do a quantitiv eanalysis. Results: Slight difference in the infection rate of H.pylori between men and women ( 95% CI:0.0579- 0.0963) was noticed. The infection rate of H.pylori in children whose parent was positive with infection of this bacteria was higher than that of children whose parent was negative ( 95% CI: 0.3378- 0.5042 ). Conclusion： The infection rate of H.pylori showed gender difference with nature of family aggregation. Epidemiological studies of H.pylori was comprehansive and involved many aspects. Further invest igation needs to be focused on infection rate and other risk factors.

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