| 王桂清,杨永举,王艳,俞学海,郭吉平,王素春,钱国正.脑血管血液动力学指标检测参数的参考值[J].Chinese journal of Epidemiology,2003,24(2):98-101 |
| 脑血管血液动力学指标检测参数的参考值 |
| The reference range of cerebrovascular hemodynamics indexes parameters |
| Received:August 27, 2002 |
| DOI： |
| KeyWord: 脑血管疾病 血液动力学 参考值 |
| English Key Word: Cerebrovascular Hemodynamics Reference range |
| FundProject:国家自然科学基金资助项目(39370612);上海市科技发展基金资助项目(934113060;944912014) |
| Author Name | Affiliation | | WANG Gui qing | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | YANG Yong ju | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | WANG Yan | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | YU Xue hai | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | Guo Ji ping | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | WANG Su chun | Shanghai Institute of Cerebral Vascular Disease Prevention and Care, Shanghai 200433, China | | QIAN Guo zheng | 第二军医大学长海医院生物医学工程研究室 |
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| Abstract: |
| 目的 对抽样人群脑血管血液动力学指标(CVHI)检测和分析,研究中国正常人CVHI的参考值范围。方法在进行中风预防干预前瞻性研究的同时,从东北、华北、西南、西北、华东、华南等六大行政区,26个城市筛选了无脑卒中病史和危险因素暴露史的正常对照者14480名(3～92岁),进行CVHI指标检测。将检测结果按照年龄、性别、地区和左右侧检测部位分组,用正态分布法计算单侧95%参考值范围。结果10对检测指标的95%参考值范围的分布特点是:颈总动脉血流速度的最大值(Vmax)、最小值(Vmin)、平均值(Vmean)的下限随着年龄的增长呈下降趋势,而脑血管外周阻力(RV)、特性阻抗(Zcv)、脉搏波波速(WV)、动态阻力(DR)、临界压(CP)等指标的上限则随着年龄的增长呈上升趋势,血流量(Qmean)和压力差(DP)无明显的年龄升降趋势;男性的Qmean、Vmax的下限和RV、DR、CP、DP的上限高于女性,而WV和Zcv的上限低于女性;左侧的Qmean、Vmean、Vmax、Vmin上限和WV、Zcv、CP的下限高于右侧,而RV、DR和DP的上限低于右侧;不同地区间各指标的分布差异无显著性。结论不同年龄、性别和左右检测部位CVHI检测指标的单侧95%参考值范围有明显差异,参考值范围应分组计算。 |
| English Abstract: |
| Objective To study the reference range of cerebrovascular hemodynamics indexes (CVHI) in a sampling population. Methods Fourteen thousand, four hundred and eighty participants without history of stroke or exposure to risk factors were screened from 26 cities in Northeast China, North China, East China, Northwest China, South China, and Southwest China in the prospective study on stroke intervention. CVHI were checked and 95% confidence intervals were calculated using normal distribution Methods, which were grouped by age, sex, area, and check positions. Results Characteristics of CVHI 95% confidence intervals showed that low limit of carotid blood velocity as Vmax, Vmin, Vmeandecreased, but upper limit of cerebral RV, Zcv, WV, DR and CP increased with the increase of age. However, Qmeanand DP did not show significant trends of age difference. Low limit of Qmean, Vmaxand upper limit of RV, DR, CP and DP in males were higher than that in females while upper limit of WV and Zcv in females were higher than that in males. Left carotid low limit of Qmean, Vmean, Vmax, Vmin, and upper limit of WV, Zcvand CP were higher than that of the right but upper limit of RV, DR and DP were lower than that of the right. There were no obvious differences between areas. Conclusion Obvious differences of CVHI 95% confidence intervals ranges were found between age groups, sex, and checking positions, respectively, suggesting that the reference ranges of CVHI to be estimated by every subgroup. |
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