| 何耀,姜勇,邢玉斌,钟光林,王磊,孙正基,贾红,常青,王勇,倪彬,陈世平.北京市某医院传染性非典型肺炎医院内感染传播途径的初步调查[J].Chinese journal of Epidemiology,2003,24(7):554-556 |
| 北京市某医院传染性非典型肺炎医院内感染传播途径的初步调查 |
| Preliminary result on the nosocomial infection of severe acute respiratory syndrome in one hospital of Beijing |
| Received:June 10, 2003 |
| DOI： |
| KeyWord: 严重急性呼吸综合征 医院获得性感染 传播途径 气溶胶传播 |
| English Key Word: Severe acute respiratory syndrome Hospital acquired infection Route of transmission Aerosol transmission |
| FundProject: |
| Author Name | Affiliation | | He Yao | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Jiang Yong | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Xin Yubin | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Zhong Guanglin | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Wang Lei | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Sun Zhengji | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Jia Hong | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Chang Qing | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Wang Yong | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Ni Bin | Chinese People's Liberation Army General Hospital, Beijing 100853, China | | Chen Shiping | Chinese People's Liberation Army General Hospital, Beijing 100853, China |
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| Abstract: |
| 目的 探讨传染性非典型肺炎 [严重急性呼吸综合征(SARS) ]医院感染的传播途径.方法 选择北京市某综合性医院 3月2～31日期间收治和医院感染的10例SARS病例,进行个案调查和发病所在科室的流行病学侦查.结果(1)发病病例的地理分布主要集中在住院大楼西单元的5个楼层的4、5号病房,住院患者多数年龄较大且合并较严重的基础病;(2)输入性病例是导致医院感染的第一代传染源,医院内继发感染的住院者是进一步扩散蔓延的第二批传染源,同时不排除隐性带病毒者(曾密切接触SARS病例而未发病者)作为潜在传染源的可能;(3)资料分析 结果支持近距离飞沫传播和密切接触传播为该次SARS医院感染的主要传播途径,同时还提示:存在气溶胶(飞沫核)经病房排风系统垂直长距离传播的可能性.结论 医院感染是SARS流行初期的主要形式.其传播途径除近距离飞沫传播和密切接触外,应进一步收集和积累是否存在气溶胶(或飞沫核)长距离传播的流行病学和实验科学证据. |
| English Abstract: |
| Objective To study the transmission route of severe acute respiratory syndrome(SARS）nosocomial infection.Methods Ten i-dentified SARS patients were selected from a general hospital in March. Survey was carried out through a standardized questionnaire pr-ovided by Chinese Center for Disease Control and Prevention. Contents of the questionnaire would include:history of contact with SARS patient route of infection methods used for protection and so on.Results (1)Distribution os SARS patients were confined to 3 w-ards:4,5,and 6 on the 7,8,12,13 and 14 floors in the west unit of the inpatient building. Most of the inpatients were elderly and hav-ing severe original diseases.(2)Index patients were the first generation source of transmission and they infected inpatients and med-ical staff making them the second generation. People with latent infection who had close contact with SARS patients might also serve as the possible source of transmission.(3)The major transmission routes were: near distant droplet infection and close contact infectio-n.There was also a clue to the probability of aerosol or droplet nuclei infection through air-conditioning and ventilation system. Conclusion Nosocomial infection appeared to be the main characteristic of the SARS epidemic in the early stage of this hospital. O-ther than close contact and transmission near space airborne transmission of SARS virus the possibility of long-distance aerosol call-ed for further epidemiological and experimental studies in the future. |
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