| 朱文丽,冯宁平,马军,王莹,叶广俊.血脂偏高学龄儿童膳食干预效果分析[J].Chinese journal of Epidemiology,2003,24(9):794-797 |
| 血脂偏高学龄儿童膳食干预效果分析 |
| The effect of dietary intervention on lipidemia in school-aged children |
| Received:July 02, 2002 |
| DOI： |
| KeyWord: 血脂偏高 膳食干预 儿童 |
| English Key Word: Hyperlipidemia Dietary intervention Children |
| FundProject:国家自然科学基金资助项目 (39770651) |
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| Abstract: |
| 目的 评价血脂偏高学龄儿童的膳食干预效果。方法 对 316名 7～ 11岁在校儿童进行血脂谱水平测定,以总胆固醇 (TC)≥ 4.2 6mmol/L或低密度脂蛋白胆固醇 (LDL C)≥ 2.2 3mmol/L确定膳食干预对象,随机分为干预组 (12 0人 )和对照组 (40人 ) ;干预组遵循低胆固醇、低饱和脂肪酸食谱方案,干预期 3个月 ;干预前后对两组人群进行膳食调查、问卷调查及体格检查 (身高、体重、皮褶厚度等 )。结果 膳食干预后干预组儿童TC、LDL C水平与对照组相比无明显改变 (干预前分别为4.6 4mmol/L和 2.6 6mmol/L,干预后分别为 4.6 8mmol/L和 2.6 2mmol/L,P >0.0 5 ),载脂蛋白A1(apoA1)水平由干预前 1378.4mg/L升高为 14 4 1.3mg/L(P <0.0 5 ) ;膳食总能量、胆固醇、饱和脂肪酸 (SFA)摄入明显减少,其中脂肪供能比由干预前的 4 0.7%下降到 31.2 %,SFA供能比已达到“膳食控制一级方案”要求 (7.7% <10 % )。此外干预组儿童健康知识水平提高,不良生活、饮食习惯改善 (总分由干预前 2 4.6上升为 2 7.4 ) ;身高增长与对照组一致。结论 对血脂偏高儿童进行以家庭为基础、以膳食调整为主的高危干预策略可有效提高血脂偏高儿童的健康知识水平,改善其不良生活及饮食习惯,同时不影响儿童的正常生长发育。 |
| English Abstract: |
| Objective To evaluate the effect of dietary intervention on lipidemia in school-aged children.Methods The levels of serum lipids profile were detected in 316 school children aged 7- 11, from those the subjects of dietary intervention were selected by total cholesterol level above 4.26 mmol/L or low density lipoprotein cholesterol level above 2.23 mmol/L.The subjects were randomly divided into intervention group (120) and control group (40). Children in intervention group were fed with low- cholesterol and low- saturated fatty acid diet, and the control group with normal diet.The duration of intervention was three months. Before and after the intervention, the food intakes, health-related questionnare and physical examination (height, weight, skinfolds thickness and so on) in the two groups were studied. Results Compared with the control group, serum cholesterol levels of children under intervention were not significantly changed (TC: 4.64 vs 4.68 mmol/L, P 0.05 ; LDL-C : 2.66 vs 2.62 mmol/L, P 0.05 ), but the apoA_1 level increased from 1 378.4 mg/L to 1 441.3 mg/L ( P 0.05 ). There were no changes for any serum lipids indexes in the control group while the dietary intakes of energy, cholesterol and SFA decreased markedly in the intervention group, with the percent of energy from fat decreased from 40.7 % to 31.2 % and SFA below to 10%( 7.7 %). Along with the increase of the scores of knowledge on health among children under intervention, the living and eating habit improved (the total scores increased from 24.6 to 27.4, P 0.05 ). The increase of height was not significantly different between the two groups. Conclusion With the family- based high- risk intervention strategy on the dietary adjustment, the knowledge on health, living and eating habit could be effectively improved in children with lipidemia.However, further research about the intervention effect on the serum cholesterol levels by strengthening the interventional degree, needs to be further studied. |
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