100例外阴白色病变患者危险因素的研究

唐桂秀; 武昕; 陈佳鹏; 周宝森

Abstract

唐桂秀,武昕,陈佳鹏,周宝森.100例外阴白色病变患者危险因素的研究[J].Chinese journal of Epidemiology,2003,24(10):932-934

100例外阴白色病变患者危险因素的研究

Study on the risk factors of 100 cases with vulvar dystrophy

Received:March 06, 2003

DOI：

KeyWord: 外阴白色病变危险因素病例对照研究

English Key Word: Vulvar dystrophy Risk facto rs Case-control study

FundProject:辽宁省科技厅基金资助项目 ( 2 0 0 1 2 2 50 0 2 1 5)

Author Name	Affiliation
TANG Gui-xiu	Departmentof Prevention, First Clinical College, China Medical University, Shenyang 110001, China
WU Xin	Departmentof Prevention, First Clinical College, China Medical University, Shenyang 110001, China
CHEN Jia-peng	中国医科大学流行病教研室
ZHOU Bao-sen	中国医科大学流行病教研室

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Abstract:

目的研究外阴白色病变的危险因素。方法调查在中国医科大学第一临床学院就诊的外阴白色病变患者100例的临床资料,按1∶1病例对照配比原则,选取工作方式、环境温度、饮食习惯、情绪、穿着内裤、自身免疫疾病、婚育史、产次、产伤、初潮年龄、经血量、外阴炎和尿道炎17个危险因素,进行单因素及多因素的logistic分析。结果多因素logistic分析显示,最终有统计学意义的因素,按危险性大小排列依次为:常患尿道炎或阴道炎者,情绪易怒、易紧张者,产次增多和喜欢吃辣食者。伴有尿道炎或阴道炎的妇女外阴白色病变发生的危险性比无此症状者增大11.02或6.74倍;情绪易怒、易紧张者外阴白色病变发生的危险性比性格开朗的人增大4.27倍;产次增多或喜欢吃辣食者外阴白色病变发生的危险性比产次少或不喜欢吃辣食者增大3.37倍或2.55倍。结论喜辣食者、易紧张或易怒者、产次增多、患阴道炎或尿道炎者是外阴白色病变的主要危险因素

English Abstract:

Objective To assess the risk factors for vulvar dystrophy. Methods An epidemiological study was car ried out.Data on 100 cases with vulvar dystrophy was reviewed and face to face interviewed with a uniform questionnaire including the manner of wo rk, environmental temperature,habit of eating, mood, underwear wearing, autoimmune diseases, marriage, menstrual age, the quantity of menses, o rders of preg nancy, and laber trauma of vulvar during delivery, vulvitis and urethritis ect.Univariable analysis and multivariate logistic regression analysis were carried out with 1∶1 case-co ntrol methodology. Results Multiple conditional logistic reg ression analysis showed tha t vulvar dy strophy was positively associated with ho t food (OR =2.55, 95%CI :1.24-5.25), mood (OR =4.27, 95 %CI :1.96-9.29), order of pregnancy (OR =3.37, 95%CI :2.11-5.40), vulvitis (OR =6.74, 95 %CI :2.66-17.09)and urethritis (OR =11.02, 95%CI :1.01-120.19).Vulviitis or urethritis increased 6.74 or 11.02 times the incidence of vulva dy strophy.Anger or nerv ous state contributed to the incidence of vulv a dy strophy (OR =4.27).Addict to ho t food and order of labo r also increased risk ratio for 2.55 and 3.37 times,respectiv ely. Conclusion The risk facto rs of vulvar dystrophy were :addict to hot food, often holding a angry o r nervous state, increase of labors, having vulvitis and urethritis.

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