证据分级评价系统及其在临床决策分析中的应用

康德英; 王家良; 洪旗; 蒋家林

Abstract

康德英,王家良,洪旗,蒋家林.证据分级评价系统及其在临床决策分析中的应用[J].Chinese journal of Epidemiology,2004,25(4):351-354

证据分级评价系统及其在临床决策分析中的应用

Evidence grading system and its usage in clinical decision-making analysis

Received:July 18, 2003

DOI：

KeyWord: 分级评价系统临床决策分析界值点NNT_(T)

English Key Word: Grading system Clinical decision making analysis Threshold NNT_(T)

FundProject:

Author Name	Affiliation
KANG De-ying	610041 成都, 四川大学华西医院临床流行病学教研室
WANG Jia-liang	610041 成都, 四川大学华西医院临床流行病学教研室
HONG Qi	610041 成都, 四川大学华西医院临床流行病学教研室
JIANG Jia-lin	四川大学公共卫生学院卫生经济学教研室

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Abstract:

目的探讨证据分级评价系统在临床决策分析中应用的可行性。方法该系统定性分级以及界值点NNT_T的估计过程,结合具体实例,进行临床决策分析。结果该例NNT_T为12,与不治疗的效应量NNT=6相比,NNT<NNT_T,表明利大于弊。结论证据分级评价系统应用过程中,正确获取不良事件的发生率以及货币化,十分关键。

English Abstract:

Objective To explore feasibility of applying evidence grading system in clinical decision- making analysis. Methods Using grading system as well as a quantitative approach to generate the threshold NNT_(T), and conducting clinical decision-making analysis through one study on Asymptomatic carotid atherosclerosis. Results NNT_(T) was 12, comparing with no-intervention in the ACA study that NNT=6. NNTNNT_(T) indicated the benefits of intervention outweigh the risks and costs. Conclusion To obtain the rate of adverse event and the specifying approximate cost were vital in the process of appklying grading system in clinical decision-making.

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