| 龚晓红,李阳桦,刘立荣,贾蕾,邢玉兰,王玉琴.北京市青少年乙型肝炎疫苗免疫效果观察[J].Chinese journal of Epidemiology,2004,25(5):388-390 |
| 北京市青少年乙型肝炎疫苗免疫效果观察 |
| Study on the afficaay of bepatitis B immunization among youngsters in Beijing |
| Received:January 16, 2004 |
| DOI： |
| KeyWord: 乙型肝炎 疫苗 青少年 免疫 效果 |
| English Key Word: Hepatitis B vaccine Callans Immune Effective |
| FundProject: |
| Author Name | Affiliation | | Gong Xiao-hong | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China | | Li Yang-hua | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China | | Liu Li-rong | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China | | Jia Lei | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China | | Xing Yu-lan | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China | | Wang Yu-qin | Department of Infectious and Endemic Diseases Control, Beijing Center for Disease Prevention and Control, Beijing 100013, China |
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| Abstract: |
| 目的: 评价青少年接种乙型肝炎(乙肝)疫苗后的流行病学效果。方法: 收集接种人群历年的接种报告、现场调查该人群的乙肝血清学流行率以及疫苗接种情况,分析接种疫苗前、后历年来乙肝发病的疫情报告, 采用放射免疫分析法测定乙肝表面抗原(HBsAg)、抗-HBs和抗-HBc, 并与接种前期的检测结果进行比较。结果: 青少年接种乙肝疫苗后, 其乙肝发病率由接种前期的12.11/10万～16.89/10万降至1.78/10万～10.95/10万(X~2=10.71～60.45,P<0.01), HBsAg携带率由6.34%降至1.37%, 下降约80.00%(X~2=14.16,P<0.01)。结论: 青少年接种乙肝疫苗是预防和控制乙肝感染的有效手段。 |
| English Abstract: |
| Objective: To evaluating the epidemiological effect atter hepatitis B immunization among youngsters in Beijing. Methods: A multistage sampling method was used for data collection from immunization cards, reports on field epidemiological survey on hepatitis B virus(HBV) immunization of youngsters and the analysisi of infectious diseases. HBsAG, nti-HBs and anti-HBc levels were detected by solid phase radiommuunoassays(SPRIA). Results: The average incidence rates of hepatitis B in 10-19 years-olds prior to HBV immunization was 12.11-16.89/100000, while declined to 1.78-10.95/100000(x2=10.71-60.45, P<0.01). HBsAg carrying rate of the youngsters decrezsed from 6.34 to 1.37% (80.00%) after vaccination (x2-14.16, P<0.01). Conclusion: Hepatitis B vaccination among youngsters is an effective measure for the prevention and control of hepatitis B virus infection. |
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