| 汤芳,李森林,詹琳,赵景平,宋文静,孔健,蒋先敏,吴晓明,杨红,张泮河,曹务春.某部队新兵营流行性脑脊髓膜炎血清流行病学调查[J].Chinese journal of Epidemiology,2005,26(11):887 |
| 某部队新兵营流行性脑脊髓膜炎血清流行病学调查 |
| Study on the distribution of Yersinia enterocolitica in Nantong,Jiangsu province |
| Received:April 28, 2005 |
| DOI： |
| KeyWord: 小肠结肠炎耶尔森菌 血清型 毒力基因 |
| English Key Word: Yersinia enterocolitica serotype Virulence gene |
| FundProject:国家“十五”科技攻关计划资助项目(2003BA712A05-04)；江苏省“135”医学重点工程资助项目 |
| Author Name | Affiliation | | GU Ling | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
| | WANG Hua | 北京军区疾病预防控制中心
| | ZHU Feng-cai | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
| | SHI Zhi-yang | 北京军区疾病预防控制中心
| | ZENG Xiao-yan | 北京军区疾病预防控制中心
| | TAN Zhao-ying | 北京绿竹生物技术有限中心 | | XIAO Yu-chun | 北京绿竹生物技术有限中心 | | QIU Hai-yan | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
| | WANG Xin | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
| | JIN Dong | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
| | GUI Zhi-gang | Jiangsu Provincial Center for Diseases Control and Prevention, Nanjing, 210009, China
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| Abstract: |
| 2005年2月, 某部队新兵营报告发生1例临床确诊流行性脑脊髓膜炎(流脑)病例, 为了解该部队流脑感染情况, 进一步做好防制工作, 我们对该部队653人进行了血清抗体检测, 调查率为96. 9%. 所有调查对象在一个月前均接种过A 群流脑多糖菌苗, 既往无流脑病史、外出史和近期类似流脑症状. 对一般情况、接触史、接种疫苗等方面内容进行问卷 |
| English Abstract: |
| Objective To study the distribution of Yersinia enterocolitica and its virulence factors in Nantong,Jiangsu. Methods Yersinia strains were isolated from livestock and poultry. Conventional PCR was used to detect the virulence factors of all strains and strains and strain 0:8 was analyzed by pulsed-field gel electrophoresis(PFGE). Results The combined isolatoin rate of Yersinia enterocolitica from livestock and poultry was 31.06% and the gene distribution characters ere:39.57% of them were ail-、ystA-、ystB-、yadA-、virF-; 60.43% were ail-、ystA-、ystB+、yadA-、virF- respectively. The two reference strains from America and Denmark showed similar electrophoresis patterns but were significantly different with 0:8 strains isolated from China while the serotypes of Yersinia enterocolitica 0:3 and 0:9 which were the main epidemic strains in China, were not found in this area. Conclusion The pathogenic Yersinia enterocolitis 0:3 and 0:9 were not found in Nantong,Jiangsu province. |
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