| 胡代玉,汪涛,刘晓云,陈静,汪洋,曾伟,徐孝芳.重庆市痰涂片阳性肺结核患者不规则服药现状及相关因素分析[J].Chinese journal of Epidemiology,2007,28(3):237-240 |
| 重庆市痰涂片阳性肺结核患者不规则服药现状及相关因素分析 |
| Study on the risk factors leading to irregularly anti—pulmonary tuberculosis drug taking in patients with smear positive |
| Received:July 17, 2006 Revised:July 17, 2006 |
| DOI： |
| KeyWord: 结核 肺 痰涂片阳性 危险因素 |
| English Key Word: Tuberculosis pulmonary Smear positive tuberculosis Risk factors |
| FundProject:世界银行贷款/英国赠款中国结核病控制项目资金资助项目(中疾控结办发03-32) |
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| Abstract: |
| 目的了解重庆市痰涂片阳性(涂阳)肺结核患者不规则服药现状及相关因素分析。方法按照社会经济发展水平和地理条件随机抽取重庆市40个区县中的4个区县，采用系统抽样方法抽取4个样本县结核病防制机构的新登记涂阳结核患者共405例进行人户调查。拟合多因素logistic回归模型探讨结核病患者不规则服药的危险因素。结果有效的401例涂阳肺结核病患者中不规则服药率为12.47%。不规则服药的前三位原因为：药物副作用(38.30%)、经济困难(23.40%)和因症状好转而停药(23.40%)。多因素logistic回归分析结果显示，自感经济负担、患病前是否知道结核病和对症状消失后能否停药的认知程度与是否规则服药之间存在有统计学意义的关联。结论结核病知识欠缺的患者更容易发生不规则服药情况，自感经济负担是影响结核病患者是否规则服药的一个重要因素。 |
| English Abstract: |
| Objective To deScribe the current situation and explore risk factorS to irregularly anti—pulmonary tuberculosis(TB)drugS taking in smear positive TB patients. Methods Four out ofthe forty counties in Chongqing were randomly sampled according to the levels of social and economic development.Totally，405 new patients with smear poSitive tuberculosis were s”tematically sampled and a household survey was carried out. Amultiple logistic regression model was fitted to explore the’risk factorS to irregularly anti—TB drugs taking. Results of valid 401 cases，50(12.47%)did not take their drugS regularly and the top 3 reasons for irregular dfllgs taking were：(1)Adverse effects；(2)Economic hardship； (3)Stopped taking drugs when symptom disappeared. Results from multiple logistic regreSsion analySis showed that factors as： self—perceived economical burden， awareness on TB befofe being infected and awareness on the fact that if anti—TB drugs can be stopped if the symptoms disappeared，were statisticany significant to irregularly drugs taking.Conclusion Strengthening health education program and alleviation of economical burden might serve as two effective measures for regularly drugs taking among TB patients. |
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