太原地区2005-2006年儿童流行性感冒病毒感染调查

兰涛; 彭桂香; 王乃昌; 常一华; 那丹宇; 张创业; 吴立平

Abstract

兰涛,彭桂香,王乃昌,常一华,那丹宇,张创业,吴立平.太原地区2005-2006年儿童流行性感冒病毒感染调查[J].Chinese journal of Epidemiology,2007,28(8):753-755

太原地区2005-2006年儿童流行性感冒病毒感染调查

Surveillance program set for influenza A virus (H1N1) in children in Taiyuan, China, 2005 - 2006

Received:April 26, 2007 Revised:August 10, 2007

DOI：

KeyWord: 流行性感冒病毒甲型急性呼吸道感染婴幼儿

English Key Word: Influenza virus A Acute respiratory infection Infants

FundProject:

Author Name	Affiliation
LAN Tao	Department of Pediatric, People's Hospital, Shanxi Province, Taiyuan 030012, China
WANG Nai-chang	Department of Pediatric, People's Hospital, Shanxi Province, Taiyuan 030012, China
CHANG Yi-hua	山西省疾病预防控制中心病毒研究室
PENG Gui-xiang	山西省疾病预防控制中心病毒研究室
NA Dan-yu	山西省疾病预防控制中心病毒研究室
ZHANG Chuang-ye	山西省疾病预防控制中心病毒研究室
WU Li-ping	山西省疾病预防控制中心病毒研究室

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Abstract:

目的了解太原地区2005-2006 年流行性感冒(流感)在儿童急性呼吸道感染中的分布并确定当年的流感病毒优势株.方法采集山西省人民医院门诊急性呼吸道感染患儿的标本87份,分别经传代犬肾(MDCK)细胞分离病毒和血凝抑制试验(HI)鉴定流感病毒型别;并于2005年10月和2006年3月(流感流行前、后期)采集415份非呼吸道疾病的儿童及部分成年人血清标本进行了流感HI抗体检测.结果从87份流感样患儿血清标本中分离出甲1型流感病毒7株,阳性率8.04%.415份血清标本中0～岁、3～岁及7～18 岁组甲1型流感HI抗体阳性率及几何平均滴度流感流行后期均明显高于流行前期,差异有统计学意义(P＜0.01).结论 2005-2006 年冬春太原地区儿童流感流行以甲1型为主.

English Abstract:

Objective To study the epidemic situation and dominant strain of influenza in children with acute respiratory infection(ARI)during Flu season from Oct.2005 to Mar.2006 in Taiyuan. Methods Madin-darby canine kidney(MDCK)cell culture and hemagglutination inhibition(HI)assay were used to isolate and identify type A influenza viruses(H1N1 and H3N2)and B influenza viruses from clinical samples collected from outpatients who visited the Department of Pediatric because of ARI from Oct.2005 to Mar.2006.Oct.2005 and Mar.2006,we collected 415’blood samples from children and adults to detect the influenza virus antibody titers by HI test to exclude respiratory diseases.Results 7 strains of H1N1 were isolated from 87 clinical specimens,with a positive rate of H1N1 as 8.04 %.Out of 415 blood samples being collected,the positive rates and the geometric mean titer of H1N1 antibody Mar. 2006 were significantly higher in 0-3,3-7 and 7-18 year-olds than Oct.2005.Conclusion H1N1 epidemic influenza did occur among children in winter and spring of 2005-2006 in Taiyuan city.

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