Abstract
胡海英,鹿斌,张朝云,茅林瑜,宋晓艳,董雪红,杨叶虹,周丽诺,李益明,赵耐青,朱禧星,王宣春,叶红英,胡仁明.上海市中心城区2型糖尿病患者视网膜病变现况调查[J].Chinese journal of Epidemiology,2007,28(9):838-840
上海市中心城区2型糖尿病患者视网膜病变现况调查
An epidemiological study on diabetic retinopathy among type 2 diabetic patients in Shanghai
Received:April 05, 2007  Revised:September 10, 2007
DOI:
KeyWord: 糖尿病    糖尿病视网膜病变  现患率  影响因素
English Key Word: Diabetes mellitus  type 2  Diabetic retinopathy  Prevalence  Risk factors
FundProject:上海市科学技术委员会重大课题资助项目(04dz19504);国家自然科学基金(39900072)
Author NameAffiliationE-mail
HU Hai-ying Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
LU Bin Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
ZHANG Zhao-yun Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
MAO Lin-yu Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
SONG Xiao-yan Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
DONG Xue-hong Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
YANG Ye-hong Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
ZHOU Li-nuo Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
LI Yi-ming Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
ZHAO Nai-qing Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
ZHU Xi-xing Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
WANG Xuan-chun Department of Endocrinology and Metabolism, Huashan Hospital, Institute of Endocrinology  
YE Hong-ying Diabetology, Fudan University, Shanghai 200040, China  
HU Ren-ming 复旦大学公共卫生学院统计教研室, 上海 200040 renminghu@fudan.edu.cn 
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Abstract:
      目的评价上海市中心城区成年人2型糖尿病患者糖尿病视网膜病变的患病率及相关因素。方法采用整群抽样方法选取上海市中心城区30岁以上已诊断为2型糖尿病的患者1039例,其中资料完整者767例纳入本研究。结果(1)767例患者完成1534张眼底摄片,其中不能分级者95例(12.4%),可以分级者672例(87.6%);(2)非增殖期糖尿病视网膜病变145例,占可分级2型糖尿病患者的21.6%,其中轻度59例(8.8%)、中度75例(11.2%)、重度11例(1.6%),增殖期糖尿病视网膜病变9例(1.3%);(3)糖尿病视网膜病变者较非病变者年龄更长,糖化血红蛋白、尿素氮和肌酐更高,逐步logistic回归分析显示糖尿病病程及空腹血糖水平为糖尿病视网膜病变的危险因素。结论上海市中心城区30岁以上已诊断2型糖尿病患者视网膜病变的现患率为22.9%,空腹血糖和糖尿病病程是影响因素。
English Abstract:
      Objective To investigate the prevalence and risk factors of diabetic retinopathy(DR) among type 2 diabetic patients aged over 30 in Shanghai central area.Methods 1039 patients diagnosed with type 2 diabetes mellitus(DM)aged over 30 were investigated by randomized cluster sampling in Shanghai central area and data from 767 of those patients were analyzed.Results(1)Among all of the 1534 digital ocular fundus images from 767 patients,87.6% of the images from 672 patients were gradable.(2)Among all of the 672 patients with gradable ocular fundus images,the prevalence of non- proliferative diabetic retinopathy(NPDR)was 21.6 %,while proliferative diabetic retinopathy(PDR)was 1.3 %.The rates of mild,moderate and severe NPDR were 8.8 %,11.2 % and 1.6 % respectively.(3) DR patients were characterized with elder age,higher HbA1c,urea nitrogen and serum creatinine.DM duration and the level of fasting plasma glucose were risk factors for DR.Conclusion The overall prevalence of DR in type 2 diabetic patients aged over 30 in Shanghai central area was 22.9 % and the DR risk factors were found to include duration of diabetes and fasting plasma glucose level.
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