Abstract
张之伦,朱向军,丁亚兴,解晓华,高志刚,李永成,张颖,夏卫东,刘勇.天津市甲型肝炎免疫预防控制措施效果评价[J].Chinese journal of Epidemiology,2007,28(10):1000-1003
天津市甲型肝炎免疫预防控制措施效果评价
Evaluation an the role of hepatitis A vaccine in the prevention and control of hepatitis A in Tianjin city
Received:May 24, 2007  
DOI:
KeyWord: 甲型肝炎疫苗  免疫预防  效果评价
English Key Word: Hepatitis A vaccine  Immune prevention  Evaluation of effectiveness
FundProject:
Author NameAffiliation
Zhang Zhilun Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Zhu Xiangjun Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Ding Yaxing Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Xie Xiaohua Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Gao Zhigang Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Li Yongcheng Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Zhang Ying Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Xia Weidong Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
Liu Yong Tianjin Centers for Disease Control and Prevention, Tianjin 300011, China 
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Abstract:
      目的 评价天津啊实施甲型肝炎(甲肝)免疫策略后控制甲肝的效果。方法 分析天津1990—2006年甲肝疫情资料,评价疫情报告系统,估算甲肝疫苗目标人群接种率,对比1999年和2005年15岁以下健康人群甲肝抗体水平。结果 天津市甲肝发病率从1990年的25.26/10万降到2006年的0.82/10万,甲肝在病毒性肝炎中的比例从1990年的30.43%降到2006年的1.05%;估算全市目标人群甲肝疫苗接种率平均为72.7%;2005年15岁以下人群甲月r抗体阳性串达到61.84%,明显高于1999年的29.90%。结论 天津市5年甲肝疫苗免疫策略的实践成功控制了甲肝流行。
English Abstract:
      Objective To evaluate the effects of prevention and control strategies on hepatitis A.Methods Surveillance data on hepatitis A from 1990 to 2006 in Tianjin was analyzed,and the coverage rate of hepatitis A vaccine among targeted population was estimated,to campare the anti-HAV IgG level of children younger than 15 years old in 1999 and in 2005.Results showed that a) the morbidity of hepatitis A decreased from 25.26/105 in 1990 to 0.82/105 in 2006;b) the ratio of hepatitis A in viral hepatitis decreased from 30.43'16 in 1991 to 1.05% in 2006;c) the estimated coverage rate was 72.7%;d) the positive rate of anti-HAV among children younger than 15 years old in 2005 was distinctly higher than that in 1999.Conclusion Positive results showed that it was successful to use hepatitis A vaccine as the strategy to prevent and control hepatitis A in the past five years in Tianjin.
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