| 朱东山,杨维中,王建军.间日疟长潜伏期研究进展[J].Chinese journal of Epidemiology,2008,29(1):81-84 |
| 间日疟长潜伏期研究进展 |
| Progress on the long incubation period of Plasmodium vivax |
| Received:June 21, 2007 Revised:June 18, 2012 |
| DOI： |
| KeyWord: 疟疾 长潜伏期 |
| English Key Word: AIDS Highly active anti-retroviral therapy Clinical compliance |
| FundProject:中英艾滋病策略支持项目(19513028) |
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| Abstract: |
| 间日疟的潜伏期一般为12-20 d[1]，长潜伏期间日疟是指在传播期被感染后不发病，经过一个长的潜伏期(一般在6个月以上)后初次发病，通常为跨年度发病。 |
| English Abstract: |
| Objective To study the clinical effect under highly active anti-retroviral therapy (HAART) in AIDS patients and for improving the curative effect and prognosis.Methods Epidemiological method was used from five aspects to describe the post-treatment clinical symptoms of 181 AIDS patients in Suizhou,and to evaluate the change of virus load and immune function of 79 AIDS patients.Data was doubly recorded by Epi Data and database was set up by SPSS 13.0 for analysis.Results The effective powers of anomal-fever,cough,diarrhoea,lymphadenectasis,weight drop,erythra, mycotic infection were 81.39%,85.00%,84.62%,81.89%,82.86%,66.07% and 45.45% respectively.CD4~+ Tlymphocyte count rose obviously after treatment,with an averag of 276× 10~6 cells/ml (65× 10~6-824× 10~6 cells/ml),an 129× 10~6 cells/ml increase in three months and was 294× 10~6 cells/ml (102× 10~6-750× 10~6 cells/ml) in six months.The count change of CD4~+ T lymphocyte between 3 months and 6 months did not show sigificant difference.The number of deaths among drug withdrawals was 14, with a case fatality rate as 29.79%;while the number of deaths among non-drug withdrawals was 3,with the case fatality rate as 2.24%.Conclusion Results through this study showed that HAART could obviously improve the clinical symptom of AIDS patients,and to increase the number of virus load. Improving the compliance could also reduce the case fatality rate. |
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