| 郑全庆,王平,惠荣,姚安梅,宿红.103例上皮性卵巢癌的预后因素分析[J].Chinese journal of Epidemiology,2008,29(1):93-94 |
| 103例上皮性卵巢癌的预后因素分析 |
| Prognostic analysis of epithelial ovarian carcinoma among 103 patients |
| Received:July 05, 2007 |
| DOI： |
| KeyWord: 卵巢肿瘤 预后因素 Cox模型 |
| English Key Word: Hemorrhagic fever with renal syndrome Occupational exposures |
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| Abstract: |
| 卵巢癌是女性生殖系统常见的恶性肿瘤之一，其中上皮性卵巢癌占原发恶性肿瘤的85%～90%.目前有关卵巢癌预后影响因素的研究很多，但在预后影响因素的认同上尚存在较大的分歧。 |
| English Abstract: |
| Objective To identify the mortality-related factors in patients undergoing maintenance hemodialysis.Methods One hundred and seven long-term hemodialysis patients having suffered from chronic glomerulonephritis and received hemodialysis treatment in the hemodialysis center of the Friendship Hospital during February 1990 to February 2002 were selected to take part in a retrospective study. Survival analysis was done using Life Tables study. Cox regression analysis was used to find factors related to risk. Patients were divided into two groups according to the clinical value of the factors which showed statistical significance in Cox regression analysis. Survive rates were compared between two groups on Gehan test.Results Among the 107 patients, 22 died (15.3%)and 85 survived (84.7%)during the follow-up period. Cumulative survival rates of 5 years and 10 years were 79.91% and 64.36% respectively. Prognostic factors would include age (P 0.001), blood urea nitrogen (BUN, P=0.004), serum creatinine (SCr, P=0.001), value of plasma calcium multiplied by plasma phosphate (P=0.019), and KT/V (P=0.001), which were all tested during the third dialysis month. The Hazard Ratios (HR) were 1.107 (95% Confidence Interval,95% CI : 1.049- 1.168), 0.951(95% CI : 0.918- 0.984), 0.727(95% CI : 0.599- 0.883), 1.025(95% CI : 1.004- 1.046), and 0.013(95% CI : 0.001- 0.161), respectively. The survival rates between two groups were significant different (age≥60 years group vs 60 years group P=0.000 6, BUN≥ 28.6 mmol/L vs 28.6 mmol/L group P=0.041 5, SCr≥884 μmol/L vs 884 μmol/L group P=0.014 6, value of plasma calcium multiplied by plasma phosphate ≥40 vs 40 group P=0.046 4, KT/V≥ 1.30 vs 1.30 group P=0.021 5).Conclusions The mortality related prognostic factors of maintained hemodialysis patients seemed to include age, BUN, SCr, value of plasma calcium multiplied by plasma phosphate, and KT/V, which were all tested during the third dialysis month. Among them, age and the value of plasma calcium multiplied by plasma phosphate were risk factors of death, while the others were protective factors. |
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