Abstract
韩晶,殷晓梅,徐斐,洪忻,梁亚琼,王志勇.南京市浦口地区高血压人群抑郁和焦虑状况的病例对照研究[J].Chinese journal of Epidemiology,2008,29(2):125-127
南京市浦口地区高血压人群抑郁和焦虑状况的病例对照研究
A case-control study on depression and anxiety in hypertensive patients
Received:August 15, 2007  Revised:June 23, 2012
DOI:
KeyWord: 高血压  抑郁  焦虑  病例对照研究
English Key Word: Hypertension  Depression  Anxiety  Case-control study
FundProject:
Author NameAffiliationE-mail
HAN Jing  cdcyxm@sina.com 
YIN Xiao-mei   
XU Fei   
HONG Xin   
LIANG Ya-qiong   
WANG Zhi-yong   
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Abstract:
      目的 了解南京市浦口地区高血压患者的抑郁和焦虑状况.方法 采用病例对照研究,抽取35岁以上高血压患者326例,健康对照414人;并使用Zung抑郁自评量表(SDS)和焦虑自评量表(SAS)评定调查对象抑郁和焦虑状况.结果 高血压病例组抑郁和焦虑自评量表的总粗分及标准分均显著高于健康对照组(P<0.01).高血压病例组的抑郁和焦虑检出率(17.9%,11.5%)均高于对照组(9.5%,4.3%),单因素分析显示抑郁、焦虑均可能是高血压的危险因素(OR=1.677,95%C/:1.013~2.776;OR=2.451,95%CI:1.228~4.894).抑郁和焦虑两者之间存在联合作用(OR=5.238,95%C/:2.356~11.664),但无交互作用.结论 高血压与抑郁和焦虑可能存在一定的关联,在高血压的预防和治疗过程中,应及时关注患者的抑郁和焦虑状况.
English Abstract:
      objective To study the current situation of depression and anxiety from patients with hypertension as well as to provide reference for the development of control and prevention program.Methods Participants older than 35-year including both hypertensive patients and healthy controls were randomly selected in 2 communities of Pukou district in Nanjing through Health Behavior Survey.All the subjects were assessed by the Zung's self-rating depression scale (SDS) and the Zung's self-rating anxiety scale (SAS).Results Raw score and index score of SDS and SAS were both significantly (P<0.01) greater in hypertensive patients than in healthy control group.The prevalence of depression of 17.90} and anxiety of 9.5 0lo in patient group were found significantly higher than that in healthy control group as 11.5 % and 4.3 %.Data from logistic regression model analysis showed that depression and anxiety were possible risk factors of hypertension(OR=1.677,95%Cl:1.013-2.776 ; OR = 2.451, 95% Cl:1.228- 4.894).There was a combined effect seen between depression and anxiety(OR=5.238,95%Cl:2.356- 11.664) but interaction did not appear.Conclusion Depression and anxiety were possibly associated with hypertension and more attention needs to be paid to the mental health situation of hypertensive patients in order to improve their quality of life.
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