| 李素梅,张根红,孙凡,王培桦,张志忠,李秀维,李淑华.饮水碘含量5～150μg/L居民户停供碘盐前后人群尿碘水平变化的干预试验研究[J].Chinese journal of Epidemiology,2008,29(8):767-770 |
| 饮水碘含量5～150μg/L居民户停供碘盐前后人群尿碘水平变化的干预试验研究 |
| Field study on the change of urinary iodine levels among family members with iodie content of 5-150ug/L in drinking water before and after non-iodized salt interwention |
| Received:February 20, 2008 Revised:June 28, 2012 |
| DOI： |
| KeyWord: 碘缺乏 碘过量 适碘地区 现场干预试验 |
| English Key Word: Iodine deficiency Iodine excess Iodine adequate areas Filed trail study |
| FundProject:首都医学发展科研基金资助项目(2002-1015) |
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| Abstract: |
| 目的<\b> 通过现场干预试验,对比观察饮用水碘含量为5～150μg/L人群停供碘盐前后碘营养水平的变化.方法<\b> 选择生活饮用水碘含量5～150μg/L的居民户作为目标居民户,用无碘盐替换其家中正在食用的碘盐,干预60 d后采集家庭成员尿样.结果<\b> 干预前学龄儿童、育龄妇女、成年男子的尿碘中位数均在370μg/L以上,频数分布≥300 μg/L的比例均在70%以上,三类人群的碘营养状况处于碘过量水平.干预后三类人群的尿碘中位数均较干预前明显下降,其中生活饮用水碘含量为5.0～99.9μg/L的人群碘营养水平下降到碘营养适宜水平或基本适宜水平;生活饮用水碘含量为100～150μg/L时,三类人群干预后的尿碘中位数仍接近300 μg/L,处于碘营养偏高状态.结论<\b> 生活饮用水水碘含景为5～100μg/L的地区为适碘地区,不需要供应碘盐;生活饮用水水碘含量为100～150μg/L的地区应划分为高碘地区. |
| English Abstract: |
| Objective To compare the change of nrinary iodine levels among the family members with iodine content of 5-150 ug/L in drinking water,before and after non-iodized salt interwention through a field trail study.Methods Faily members who routinely drank water with iodine content 5-150ug/L were chosen to substitudte non-iodized salt for their current iodized salt for 2 months,and urine samples of the family members were collected for deteemination of iodine change before and after intervention was carried out.Results Median urinary iodine of school children, women with productive age and male adults exceeding 370ug/L before intervention and the frequency distribution of unrinary iodine were all above 70%. Our results revealed that iodine excess exited in three groups of family members.After intervention,all median urinary iodine level seemed to have decreased significantly,and groups with drinking water iodine 5.0-99.9ug/Ｌ reduced to adequate or close to adequate while the group that driking water iodine was 100-150 ug/L reached the cut-off point of excessive iodine level. |
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