| 解武祥,曹卫华,林军.老年肥胖与心血管病主要危险因素聚集的关系[J].Chinese journal of Epidemiology,2008,29(10):975-978 |
| 老年肥胖与心血管病主要危险因素聚集的关系 |
| Study on the relationship between obesity and clustering of major risk factors on cardiovascular diseases in the elderly |
| Received:May 21, 2008 |
| DOI： |
| KeyWord: 肥胖 心血管疾病 老年人 危险因素聚集 |
| English Key Word: Obesity Cardiovascular diseases Elderly CInstering of risk factors |
| FundProject: |
| Author Name | Affiliation | | XlE Wu-xiang | Department of Epidemiology and Statistics, School of Public Health, Peking University Health Science Center, Beijing 100083, China | | CAO Wei-hua | Department of Epidemiology and Statistics, School of Public Health, Peking University Health Science Center, Beijing 100083, China | | LlN Jun | Department of Epidemiology and Statistics, School of Public Health, Peking University Health Science Center, Beijing 100083, China |
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| Abstract: |
| 目的 探讨老年人肥胖与发生心血管疾病主要危险因素聚集之间的相关关系.方法 采用横断面调查546名60～90岁的老年人,用描述性统计方法、logistic回归和ROC工作曲线法进行相关分析. 结果 (1)四种危险因素及危险因素聚集的检出率随着BMI、腰围(WC)水平的上升而增加,危险因素聚集检出率为59.5%,其中男性组为52.5%,女性组为65.7%.(2)随着BMI和(或)WC水平的上升,老年男性发生危险因素聚集风险的增长速度要高于女性,其中男性最高水平组OR值为13.579,女性组为2.876.(3)男性BMI和WC均与危险因素聚集存在独立的相关性(P<0.05),logistic回归系数分别为bBMI=0.196,bWC=0.074;女性只有WC与危险因素聚集存在独立的相关性(P<0.05),logistic回归系数为bWC=0.060,而BMI与危险因素聚集不存在独立的相关性(P=0.537).(4)男性的BMI和WC组合公式(CE)为CEBMI+WC=0.726×BMI+0.274×WC,最佳截断值为41.59,其灵敏度和特异度分别为0.785和0.598. 结论 四种主要的心血管病危险因素经常伴随着肥胖出现,BMI和WC对于心血管疾病的一级预防具有重要意义,两者的组合公式可用于预测个体的心血管疾病危险因素聚集风险. |
| English Abstract: |
| Objective To study the correlation between obesity and clustering of major risk factors on cardiovascular disease in the elderly.Methods A cross-sectionai study was conducted.Data from 546 elderlY aged 60-90 were analyzed for the relationship between obesity and clustering of risk factors for cardiovascular diseases,with descriptive statistical methods,x2 test,logistie regression and ROC curve．Results (1)The positive rates of the four major risk factors and clustering appeared an upward trend along with the BMI and or the wc.The overall positive rate of clustering of risk factors among the total 546 elderly people was 59.5％,and 52.5％in males,65.7％in females.(2)As compared with females,males had a higher growth rate of clustering with the elevating of BMI and WC.and odds ratios of the highest-level groups were 13.579 and 2.876 in males and females.Respectively.(3)Both BMI and WC were independent influencing factors for male(P<0.05),and logistic regression coefficients were 0.196 and 0.074 for BMI and WC,respectively.Only WC appeared to be the independent influencing factor for females(P<0.05),while BMI WaS not(P:0.537),with logistic regression coefficient as 0.060 for WC.(4)The combination equation of male's BMI and WC Was CEBMI+WC=0.726 × BMI+0.274 × WC,with the optimum cut-off value as 41.59,and the sensitivity and the specificity were 0.785 and 0.598,respectively．Conclusion Four major risk factors for cardiovascular diseases were often related to obesity while control of BMI and WC were of great significance to the primary prevention of cardiovascular disease．The combined equation of BMI and WC could be used to predict the risk of clustering. |
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