中国1998—2007年肾综合征出血热流行病学特征及疫苗接种策略探讨

罗成旺; 陈化新

Abstract

罗成旺,陈化新.中国1998—2007年肾综合征出血热流行病学特征及疫苗接种策略探讨[J].Chinese journal of Epidemiology,2008,29(10):1017-1019

中国1998—2007年肾综合征出血热流行病学特征及疫苗接种策略探讨

Epidemiological characteristics and the strategy of vaccination on hemorrhagic fever with renal syndrome in the last 10 years,in China

Received:June 15, 2008

DOI：

KeyWord: 肾综合征出血热疫苗接种策略流行病学

English Key Word: Hemorrhagic fever with renal syndrome Vaccination Strategy Epidemiology

FundProject:

Author Name	Affiliation
LUO Cheng-wang	National Institutefor Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China
GUO Xiao-xin	National Institutefor Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China

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Abstract:

目的分析1998—2007年全国肾综合征出血热(HFRS)人间疫情流行病学特征。方法对1998—2007年中国HFRS人间疫情进行统计，采用描述流行病学方法进行空间、时间和人群分布分析。结果1998—2007年全国HFRS人间疫情的空间分布具有既分散又相对集中的特点，病例主要分布在山东、黑龙江、辽宁、河北、陕西、湖南、吉林、浙江等省，占全国总发病数的81．76％；HFRS时间分布具有明最的季节性，一般有春季和秋冬季两个流行高峰期，高峰期各月的发病数占全年发病数的10．00％以上。HFRS人群中，<10岁的病例占0．97％、10～70岁的病例占96．71％、15～60岁的病例占87．32％、≥70岁的病例占2．31％；男、女之比为3：1；从职业构成来看，农民占70．00％，为主要发病人群。结论近10年来中国HFRS的三间分布特点可作为HFRS疫苗免疫接种策略的科学依据，建议根据疫区性质，做好重点地区、重点人群和疫苗类型的选定工作。

English Abstract:

objective To study the epidemiologieal characteristics and vaccination strategy of hemorrhagic fever with renal syndrome(HFRS)in China。from 1998 to 2007．Methods National data on the prevalence of HFRS during 1998 to 2007 were collected and analyzed．Spatial,time and population distributions of HFRS case were described．Rcsults HFRS appeared to ramain endemic in the country． while the majority of cases(accounting for 81．76％of total eases)，were located in Shandong，Heilongjiang， Liaoning，Hebei，Shanxi，Hunan，Jilin and Zhejiang provinces．The occurrence of HFRS appeared to be seasonal,with two peaks in spring season and autumn／winter season，with 10.00％of the cases occurrcd in these peak months．The incidence rates were at a relatively low level because of the continuous decline of HFRS in the recent years．With age distribution，0．97％were younger than 10。96．71％were between 10 and 70,87．32％were between 15 and 60，and 2．31％were older than 70．The proportion of male patients accounted for three quarters．Around 70．oo％of the cases were farmers．Young and middle—agcd male farmers were at high risk．Conclusion The descriptive study on epidemiological characteristics of HFRS in the recent years had provided scientific evidence for vaccination strategy，suggesting the key regions，sub- populations as well as types of vaccines be determined．

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