| 杨智聪,毛新武,李铁钢,李海麟,刘于飞,吴新伟,袁俊,谢朝军,李魁彪,蒋丽云,陈艺韵,湛柳华,肖晓玲,刘建平,沈纪川,蔡文峰,王鸣.国内首起本地感染甲型H1N1流感疫情的流行病学分析[J].Chinese journal of Epidemiology,2009,30(7):684-686 |
| 国内首起本地感染甲型H1N1流感疫情的流行病学分析 |
| Epidemiological charaeteristic of first case of Iocally identmed A/HlNl secondary casea caused by imported source of tnfection in China |
| Received:June 02, 2009 |
| DOI：10.3760/cma.j.issn.0254-6450.2009.07.009 |
| KeyWord: 甲型HINl流感 本地感染 流行病学特征 |
| English Key Word: HlNl Autochthonous infection Epidemiologic feature |
| FundProject: |
| Author Name | Affiliation | E-mail | | YANG zhicong | 510080,广州市疾病预防控制中心 | | | LI Tiegang | 510080,广州市疾病预防控制中心 | | | LIU Yufei | 510080,广州市疾病预防控制中心 | | | WU Xinwei | 510080,广州市疾病预防控制中心 | | | YUAN Jun | 510080,广州市疾病预防控制中心 | yjk@gzedc.org.cn | | XiE Chaojun | 510080,广州市疾病预防控制中心 | | | LI Kuibiao | 510080,广州市疾病预防控制中心 | | | JIANG Liyun | 510080,广州市疾病预防控制中心 | | | CHEN Yiyun | 510080,广州市疾病预防控制中心 | | | MA0 Xinwu | 510080,广州市疾病预防控制中心 | | | LI Hailin | 510080,广州市疾病预防控制中心 | | | ZHANG Liuhua | 广州中越秀区疾病预防控制中心 | | | XIAO Xiaoling | 广州中越秀区疾病预防控制中心 | | | LIU Jianping | 510080,广州市疾病预防控制中心 | | | SHEN Jichuan | 510080,广州市疾病预防控制中心 | | | CAl Wenfeng | 510080,广州市疾病预防控制中心 | | | WANG Ming | 510080,广州市疾病预防控制中心 | |
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| Abstract: |
| 目的 分析周内首起甲型HINl流感输入性传染源引发本地二代病例疫情, 探讨发病规律和流行特征。方法 设计统一调查表, 采用面对面病例个案调查和现场调查, 以指示病例为起点进行追踪, 描述传播过程及各因素与发病之间的关系, 分析疫情的流行病学特征。结果 发现指示病例后, 密切接触者中有2人出现发热和上呼吸道症状且咽拭子甲型HINI流感病毒核酸检测阳性, 被确诊为国内茸起本地感染甲趔H1Nl流感病例。2名密切接触者未采取任何防护措施与指爪病例多次近距离接触, 且现场通风不良;发病潜伏期37～57 h, 临床表现均较指示病例轻。经采取严格防疫措施, 未见新发病例。结论 此次事件为由输入性传染源引起的本地感染疫情, 无防护近距离空气及飞沫传播为主要传播方式, 空气流通不良的密闭李间是高危场所。 |
| English Abstract: |
| Objective To study the first locally identifed A/HlNl secondary cases outbreak in China.Methods Interview and field investigation were integrated to describe the whole process of transmission on each case and to illustrate the relationships between the onset of the disease and the retated factors.Results Two contact persons appearanced fever and whose throat swabs were tested positive to HlN1 viral nucleic acid.The two had ahistory of contact in a short distanee with the initial imported case without any protective measure in the poor air ventilation.The patients clinical situation was slight.The incubation was between 37 hours and 57 hours.N0 other newcase was found after intervention as isolation and antisepsis were taken.Conclusion This event was proved to be an outbreak of local H1Nl secondary cases caused by the imported case.The main mode of transmission was personal contact in a short distance without protection, through air and droplet.The lOCUS with poor air ventilation was high risk place.Contact persons should be observed seven days and tested continuously.1nfectivity and pathogenicity of the A/HlN1 virus were limited and appeared weakened by ations.Patient’s condition was related with persistence and frequency of contact with the infection sources.Enhancing management of contact persons, health education。early diagnose, early treatment and early insulation were effective measures of controling and prenventing the spread A/H1N1. |
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