| 张波,蔡莉,苏萌,周晓星,黄莉莉,陈超刚,甘人友,陈若青,苏宜香.广州市40~65岁中老年人膳食大豆异黄酮摄入与血脂关系的横断面研究[J].Chinese journal of Epidemiology,2009,30(8):761-765 |
| 广州市40~65岁中老年人膳食大豆异黄酮摄入与血脂关系的横断面研究 |
| Relationship between dietary soy isoflavones and blood lipid levels in 40-65 year-olds in Guangzhou |
| Received:February 17, 2009 |
| DOI： |
| KeyWord: 血脂 大豆异黄酮 食物频数问卷 |
| English Key Word: Blood lipids Soy isoflavone Food-frequency questionnaire |
| FundProject: |
| Author Name | Affiliation | E-mail | | ZHANG Bo | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | CAI Li | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | SU Meng | 中山大学公共卫生学院预防医学系, 广州, 510080 | | | ZHOU Xiao-xing | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | HUANG Li-li | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | CHEN Chao-gang | 中山大学公共卫生学院附属第二医院营养科, 广州, 510080 | | | CAN Ren-you | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | | | CHEN Ruo-qing | 中山大学公共卫生学院预防医学系, 广州, 510080 | | | SU Yi-xiang | Department of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China | suyx@mail.sysu.edu.cn |
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| Abstract: |
| 目的 研究广州市中老年人大豆异黄酮摄入与血脂的关系.方法 用食物频数问卷分析395名40～65岁广州市居民每日大豆异黄酮及其他食物和营养素的摄入量,抽取空腹静脉血测定血脂.结果 134名男性和261名女性的大豆异黄酮摄入分别为11.95(0～61.96)mg/d和14.90(0～82.52)mg/d.按照大豆异黄酮摄入量将研究对象等分为低、中、高三组,在校正了总能量摄入和脂肪供能比后,三组间TC、LDL-C差异有统计学意义(P值分别为0.002、0.008),并存在剂量效应关系(趋势分析P值分别为<0.001、0.012);高摄入组与低摄入组相比,TC、LDL-C分别下降7.06%、10.13%.在进一步校正年龄、BMI和腰臀比后,上述结果无明显改变.结论 膳食大豆异黄酮摄入与血浆TC、LDL-C负相关. |
| English Abstract: |
| Objective To study the mlationship between dietary soy isoflavones and blood lipids among residents of 40-65 years old,in Guangzhou.Methods Dietary soy isoflavones and other nutrients intakes were assessed with quantitative food frequency questionnaire(FFQ).Total cholesterol(TC),triglycerides(TG),HDL cholesterol(HDL-C)and LDL cholesterol(LDL-C)in plasma were measured with colorimetry.Results Ranges of dietary soy isoflavones intake among 134 males and 261 females were fxom 0 mg/day to 61.96 mg/day and 0 mg/day to 82.52 mg/day,with means of 11.95 mg/day,14.90 mg/day,respectively.After adjusted for total energy intake and fat percent energy,difiefences of TC,LDL-C in total population and TC in women were statistically significant between groups(P value was 0.002,0.008,0.004,respectively) and dose-effect relationships(P value was <0.001.0.012.0.001,respectively)were observed between dietary soy isoflavones intake and the upper mentioned three indices.Compared with the low-intake group,tbese three indices lowered 7.06%,10.13%and 7.48%,respectively in high-intake group.Critical significance of LDL-C was observed both in women and men between groups.Further controlled for age,BMI and WHR,no obvious change of the results was observed.Conclusion Moderate intakes of soy isoflavone as part of a regular diet seemed to be associated with favorable blood lipid levels. |
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