| 陆益花,严建华,孙瓅贤,李全,王燕杰,庄勋,张泽峰,范中杰.冠状动脉介入术对冠心病患者生活质量影响的协方差分析[J].Chinese journal of Epidemiology,2010,31(1):87-91 |
| 冠状动脉介入术对冠心病患者生活质量影响的协方差分析 |
| Covariance analysis on the change of quality of life affected by percutaneous coronary intervenfion for patients with coronary heart disease |
| Received:July 30, 2009 |
| DOI： |
| KeyWord: 冠心病 经皮冠状动脉腔内成形术 生活质量 |
| English Key Word: Coronary heart disease Percutaneous coronary intervention Quality oflife |
| FundProject: |
| Author Name | Affiliation | E-mail | | LU Yihua | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China
School of Public Health. Nantong University | | | YAN Jianhua | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China | | | SUN Lixian | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China | | | LI Quan | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China | | | WANG Yanjie | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China | | | ZHUANG Xun | School of Public Health. Nantong University | | | ZHANG Zefeng | School of Public Health. Nantong University | | | FAN Zhongjie | Division ofCardiology Peking Uniom Medical College Hospital, Chinese Academy of Medical Science, Beijing 100730, China | zhifan@hotmail.com |
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| Abstract: |
| 目的联合使用两种生活质量问卷sF一36和QOL一35，评价冠心病患者经皮冠状动脉腔内成形术(PCI)后3个月生活质量变化，探讨PCI对冠心病患者生活质量的影响。方法连续观察2008年3月在北京协和医院心内科住院患者6l例，按照是否行PCI将患者分为两组。使用sF一36和QOL一35对患者生活质量进行评估，3个月后随访患者并再次评测生活质量，采用多元协方差分析评估PCI对冠心病患者生活质量的影响。结果24例非PCI组患者和37例PCI组患者性别(P=0.005)、心绞痛发作史(Jp=O.015)、吸烟史(P=0.037)和冠状动脉狭窄程度Judkins分级(P=0.001)的差异有统计学意义，其他临床基线资料的差异无统计学意义。用多元协方差分析控制基础水平的差异后，比较PCI对患者生活质量的影响，PCI对两组SF一36总分(P=0.044)、精神健康领域得分(P=0.003)、QOL一35总分(P=0.039)、社会功能领域得分(P=O.007)影响的差异有统计学意义。结论PCI能提高冠心病患者的生活质量。 |
| English Abstract: |
| Objective To compare changes of quality of life at 3 months from baseline among patients who underwent and did not undergo pcrcntaneous coronary intervention(PCI).Methods Sixty one patients with coronary artery disease.who were hospitalized in Cardiology Department in March 2008，were followed.up for 3 mortths after being discharged.SF-36 and 00L一35 were administered before PCI and at 3 months.Patients were divided into 2 groups according to whether they underwent PCI.Changes of quality of lire scores between PCI and non.PCI groups were compared USing analysis of covafiance.Results<5/b> There were 24 cases in non—PCI group and 37 in PCI group.Baseline characteristics were well balanced between PCI and non.PCI groups except gender(67.6％135.28.6％for male，P=0.005)。history of angian(56.8％735.23.8％，P=0.015)， smoking history(51.4％铝.23.8％。P=O.037)and Judkins classification of coronary artery(P=0.001).Multivariate analysis of covariance showed that the change of life quality between non-PCI group and PCI group in 3.months after discharge had statistical differences in total scores(Jp=O.044)and mental health scores(P=0.003)of SF一36，total scores(P=0.039)and social function scores(P=0.007)of Q0L一35.Conclusion PCI Can improve life quality in patients with coronary artery disease. |
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