| 陈梦施,杨华林,陈艳芳,谭红专,白丽琼,张艳辉,刘军,李桂平.湖南省HIV/AIDS人群结核发病影响因素的巢式病例对照研究[J].Chinese journal of Epidemiology,2010,31(2):151-154 |
| 湖南省HIV/AIDS人群结核发病影响因素的巢式病例对照研究 |
| A nested case·control study on the influencing factors of tuberculosis among people living withHIV/AIDS in Hunan province |
| Received:August 03, 2009 |
| DOI： |
| KeyWord: 艾滋病 结核 巢式病例对照研究 影响因素 |
| English Key Word: Acquired immunedeficiency syndrome Tuberculosis Nested case-control study Influencing factors |
| FundProject:全球基金中国结核病实施性研究(07-062) |
| Author Name | Affiliation | E-mail | | CHEN Meng-shi | Department of Epidemiology, School of Public Health, Central SouthUniversity, Changsha 410078, China | | | YANG Hua-Lin | Hunan Institute for Tuberculosis Control | | | CHFN Yan-fang | Yueyanglou Centerfor Disease Control and Prevention | | | TAN Hong-zhuan | Department of Epidemiology, School of Public Health, Central SouthUniversity, Changsha 410078, China | tanhz99@qq.com | | BAI Li-qiong | Hunan Institute for Tuberculosis Control | | | ZHANG Yan-hui | Department of Epidemiology, School of Public Health, Central SouthUniversity, Changsha 410078, China | | | LIU Jun | Hengyang Centerfor Disease Control and Prevention | | | LI Gui-ping | Qidong Centerfor Disease Control and Prevention | |
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| Abstract: |
| 目的探讨HIV/AIDS人群发生结核病的危险因素。方法采用1:2匹配的巢式病例对照研究方法分析HW/AIDS人群发生结核的危险因素。结果对1018例未患结核的HIV/AIDS人群随访观察1年，累计观察736.75人年，共检查出结核病患者62例，HIV/AIDS人群结核病发病密度为8.42A/100人年(62人/736.75人年)。文化程度(OR=O.483)、卡介苗接种史(OR=0.561)、CD。+T淋巴细胞数(OR=O.356)、无业(OR----1.976)、单身(OR=2.646)和吸烟(OR=2.215)等因素与HIV/AIDS人群发生结核病有关。结论文化程度高、有卡介苗接种史和CD4+T淋巴细胞数高是HIV/AIDS人群患结核病的保护因素；无业、单身和吸烟是HIV/AIDS人群患结核病的危险因素。 |
| English Abstract: |
| Objective To determine the risk factors related to tuberculosis infection among people living with HIV/AIDS and to develop strategies for preventing the CO-infection.Methods A 1:2matched nested case.control study was can-/ed out to analyze the influencing factors of tuberculosis among people living with HIV/AIDS.Results 1018 people living with HIV/AIDS were followed up
for one year with a total number of 736.75 person.years。among them 62 tuberculosis cases were diagnosed.The incidence density of tuberculosis among people living with HIV/AIDS Was 8.42persons per 100 person-years.Factors as education level(0R=0.483)。vaccination history ofBacille Calmette Guerin(OR=O.561)。CD4count T-lymphocyte(OR=O.356)，unemployment(OR=1.976)，living alone(0R=2.646)。and smoking(OR=2.215)were significantly related to the prevalence of tuberculosis among people living with HIv/AIDS.Conclusion High education level，with vaccination history of Bacille CalmeRe Guerin and high level of CD4+T-lymphocyte count were protective factors while being unemployed，living alone，and smoking habit were risk factors related to the prevalence of tuberculosis among people living with HJV/AIDS. |
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