全基因组关联研究与复杂疾病风险预测的现状与展望

沈洪兵; 靳光付

Abstract

沈洪兵,靳光付.全基因组关联研究与复杂疾病风险预测的现状与展望[J].Chinese journal of Epidemiology,2011,32(7):643-649

全基因组关联研究与复杂疾病风险预测的现状与展望

Genome．wide association study(GWAS)and risk prediction of complex disease：advances and prospects

Received:April 15, 2011

DOI：

KeyWord: 遗传标志物遗传风险风险预测全基因组关联研究基冈组流行病学

English Key Word: Genetic marker Genetic risk risk prediction Genome—wide association study Genome epidemiology

FundProject:

Author Name	Affiliation	E-mail
SHEN Hong-bing	Depertment of Epiderniology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China	hbshcn@njmu．cdu．cn
JIN Guang-fu	Depertment of Epiderniology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing 210029, China

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Abstract:

人类基因组计划(human genome project，HGP)的完成预示着生命科学研究进入了基因组时代，在利用基因组学方法进行流行病学研究的过程中产生了基因组流行病学。在人群中研究与疾病发生发展或健康相关的遗传变异，即遗传标志物(genetic marker)用于疾病的预防和治疗、促进健康，是基因组流行病学的主要研究内容.

English Abstract:

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