Abstract
周宗立,张建平,汪小敏,邵祺,胡佳圆,韩庆东.甲真菌病患者外用抗真菌药治疗的依从性及影响因素调查[J].Chinese journal of Epidemiology,2011,32(7):720-723
甲真菌病患者外用抗真菌药治疗的依从性及影响因素调查
Compliance of the patients and related influential factors on the topical antifungal treatment of onychomycosis
Received:January 10, 2011  
DOI:
KeyWord: 甲真菌病  外用药治疗  依从性  影响因素
English Key Word: Onychomycosis  Topical treatment  Adherence  compliance  Influencing factors
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Author NameAffiliationE-mail
ZHOU Zong-li Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China zhouzongli74@sohu.com 
ZHANG Jianping Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China  
WANG Xiao-min Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China  
SHAO Qi Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China  
HU Jia-yuan Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China  
HAN Qing-dong Department of Dermatology and Venerology, the Second Hospital of Jiaxing, Zhejiang, Jiaxing 314000, China  
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Abstract:
      目的了解甲真菌病患者外用抗真菌药治疗的依从率及其影响因素。方法对所有同意参与调查的甲真菌病患者采用皮肤病患者生活质量调查表和自编调查表调查。结果甲真菌病患者使用外用药治疗的依从率为23.9%(92/385)。依从性良好者的甲真菌病治愈率为63.04%(58/92),而依从性不良者治愈率为2.05%(6/293)。在所有的调查因素中,年龄、性别、文化程度、职业、病程、家庭人均收入、不方便就医或用药、经常忘记用药、疗程长耐心不足、对治疗信心不足、感觉外用药“脏”、嫌麻烦以及生活质量评分等因素与外用药治疗因素有显著相关,担心药物不良反应、患甲数目、患甲部位、无时间用药、相关知识缺乏以及其他因素,在依从性不良和良好者间的差异无统计学意义。结论甲真菌患者外用药治疗依从性低且对疗效影响显著,年龄、性别、文化程度、职业、病程、家庭人均收入、不方便就医或用药、经常忘记用药、疗程长耐心不足、对治疗信心不足、感觉外用药“脏”、嫌麻烦以及生活质量评分等闲素与依从性显著相关。
English Abstract:
      Objective To explore the compliance rate of patients and its influential factors on topical antifungal treatment of onychomycosis.Methods Dermatology life quality index(DLQI)and self-administered questionnaires were employed in this study.Results The overall compliance rate of the topical antifungal treatment WaS 23.9%(92/385).The cure rates on onychomycosis in patients witll good compliance was 63.04%(58/92),but only 2.05%(6/293)in those noneompliant patients,respectively.Regarding the influencing factors as age。sex,level of awareness,occupation,course of disease.personal income.inconvenience in access to the treatment.keep forgetting in taking the medicine,being impatient,lack of confidence,misunderstanding on topical as‘dirty’and the process of drug taking was troublesome.together with the quality of lire were identified.There were significant differences between those compliant or noncompliant patients.For some factors as adverse effects of drug,numberofaffected nails。site ofthedisease,tOO busyin dailylife。lack ofrelatedknowledge etc.,no significant differences were fo·und between the compliant or noncompliant patients.Conclusion Our results showed that onychomycosis patients had poor compliance in topical antifungal treatment which significantly influencing the therapeutic effects.Age,sex,level of awareness on the diseaSe,occupation,course of disease,personal income,inconvenience in receiving the treatment,forgetting to take the medicine,lack of patience,lack of confidence,different kinds of misunderstanding about the disease and quality of lire etc.might affect the compliance rate ofthe disease.
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